Publications by authors named "Ivan Gutierrez-Tobar"
Eikenella corrodens and Streptococcus sanguinis are indigenous to the oral cavity and infrequently associated with osteoarticular infections. We detail a case of septic arthritis in a 13-year-old boy who suffered a puncture wound with a toothpick after eating. This case highlights the ability of these microorganisms to instigate osteoarticular infections through penetrating trauma and not only through the hematogenous route.
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- Infections significantly impact pediatric health worldwide, prompting the Staphylo Research Network to study pediatric patients in Colombia between 2018 and 2021, focusing on their epidemiological and microbiological characteristics.
- The study analyzed 8,157 culture isolations from 20 centers, noting that methicillin-sensitive Staphylococcus aureus (MSSA) was more common than methicillin-resistant Staphylococcus aureus (MRSA), particularly in different regional hospitals.
- Findings highlight that while MSSA was dominant, regional variations in MRSA prevalence exist, and most strains showed susceptibility to common antibiotics, emphasizing the need for ongoing infection monitoring in children.
Introduction. During the SARS-CoV-2 pandemic, many countries experienced decreased respiratory virus circulation, followed by an out-of-season outbreak. In a pediatric hospital in Colombia, we observed a surge in severe adenovirus infections, leading to concerns about the impact of eased public health restrictions and immune debt in children under five years old.
View Article and Find Full Text PDFThe microbiological diagnosis of pleural effusion is based largely on classical microbiology methods, but these methods have a high rate of false negative results. Some previous studies have shown improved diagnostic performance for pathogens such as using molecular biology methods. We present the use of a multiplex PCR platform (BIOFIRE FILMARRAY Pneumonia Panel) for the aetiological diagnosis of pleural effusion in paediatric pneumonia.
View Article and Find Full Text PDFMultinational prospective cohort study of incidence and risk factors for central line-associated bloodstream infections in ICUs of 8 Latin American countries.
Am J Infect Control
October 2023
Article Synopsis
- The study aimed to identify rates and risk factors for central line-associated bloodstream infections (CLABSI) in 58 ICUs across 8 Latin American countries from 2014 to 2022.
- A total of 29,385 patients were observed, leading to a CLABSI rate of 4.30 per 1,000 central line days, with significant risk linked to longer hospital stays, more central line days prior to infection, and infections occurring in publicly-owned facilities.
- The research suggests targeting strategies to reduce length of stay and central line days, and replacing high-risk femoral and internal-jugular lines with PICC lines to mitigate CLABSI risks.
First publication of endemic channels as part of a pediatric Antimicrobial Stewardship Program: when to turn on the alarms? Recommendations of a pediatric ASP program.
BMC Infect Dis
January 2023
Article Synopsis
- Pediatric Antimicrobial Stewardship Programs (ASP) use Days of Therapy (DOT) to assess their impact, but novel endemic channels (EC) have not been previously established to compare antibiotic usage over time.
- A descriptive study created and analyzed these ECs, using statistical methods to evaluate changes in antibiotic use, particularly focusing on critical services like the Pediatric Intensive Care Unit (PICU).
- Results showed that the geometric mean and confidence interval methods effectively identified shifts in antibiotic prescriptions, allowing for timely interventions in response to changing patterns of disease and treatment guidelines, making ECs a valuable tool for ASPs in both pediatric and adult settings.
Multinational prospective cohort study over 24 years of the risk factors for ventilator-associated pneumonia in 187 ICUs in 12 Latin American countries: Findings of INICC.
J Crit Care
April 2023
Epidemiological characteristics and serotype distribution of culture-confirmed pediatric pneumococcal pneumonia before and after PCV 10 introduction, a multicenter study in Bogota, Colombia, 2008-2019.
Vaccine
May 2022
Article Synopsis
- - PCVs have helped reduce pneumonia in children, with Colombia starting mass vaccination using PCV10 in 2012, leading to the comparison of pneumonia cases before (2008-2011) and after (2014-2019) vaccination.
- - The study analyzed 370 cases revealing a significant drop in occurrences of serotypes 1 and 14, while serotypes 19A, 3, and 6A surged, indicating more serious cases needing increased hospital care and longer antibiotic treatment.
- - Findings suggest that PCV10 decreased specific serotypes but allowed for the rise of more severe strains, emphasizing the need for transitioning to a more effective vaccine like PCV13 to combat evolving pneumonia challenges.