Publications by authors named "Ivan D Ocampo"

Immune recognition of molecular patterns from microorganisms or self-altered cells activate effector responses that neutralize and eliminate these potentially harmful agents. In virtually every metazoan group the process is carried out by pattern recognition receptors, typically constituted by immunoglobulin (Ig), leucine rich repeat (LRR), and/or lectin domains. In order to get insights into the ancestral immune recognition repertoire of animals, we have sequenced the transcriptome of bacterially challenged colonies of the model cnidarian Hydractinia symbiolongicarpus using the Illumina platform.

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Article Synopsis
  • Glucose 6-phosphate dehydrogenase (G6PD) is crucial for protecting red blood cells from oxidative damage, with a significant number of people worldwide, particularly in malaria-endemic areas, having varying degrees of G6PD deficiency (G6PDd) that can lead to hemolysis, especially when treated with drugs like primaquine (PQ).
  • A study in Colombia evaluated G6PDd prevalence among 426 volunteers from four malaria-endemic regions, using blood samples to measure enzymatic activity and analyze genotypes; 6.56% of participants showed G6PDd, with the highest prevalence in Buenaventura.
  • The results indicated a notable frequency
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The viability of coral reefs worldwide has been seriously compromised in the last few decades due in part to the emergence of coral diseases of infectious nature. Despite important efforts to understand the etiology and the contribution of environmental factors associated to coral diseases, the mechanisms of immune response in corals are just beginning to be studied systematically. In this study, we analyzed the set of conserved immune response genes of the Caribbean reef-building coral Pseudodiploria strigosa by Illumina-based transcriptome sequencing and annotation of healthy colonies challenged with whole live Gram-positive and Gram-negative bacteria.

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