Publications by authors named "Iva Kusec"
Materials (Basel)
September 2021
Article Synopsis
- The study examines the structure and interactions of aminopropyl-azithromycin derivatives using NMR spectroscopy and docking calculations, which are important for developing new antibiotics against resistant bacteria.
- The compounds exist in specific conformations in both solution and solid states, and their binding to the ribosome plays a critical role in their potential effectiveness.
- Docking studies reveal that these derivatives bind to the same ribosome site as erythromycin, utilizing hydrogen bonds and van der Waals interactions, enhancing understanding of their binding mechanisms.
