Publications by authors named "Iva Jirka"
Background: Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), a gastric precancerous lesion, is of growing interest for identification of patients at increased risk of gastric cancer. The aim was to analyze the diagnostic performance of serum pepsinogen testing using another method, chemiluminescent enzyme immunoassay (CLEIA), as well as of other new potential biomarkers.
Material And Methods: The sera of patients considered at increased risk of gastric cancer and undergoing upper endoscopy collected in our previous prospective, multicenter study were tested for pepsinogen I (PGI) and II (PGII), interleukin-6 (IL-6), human epididymal protein 4 (HE-4), adiponectin, ferritin and Krebs von den Lungen (KL-6) using the CLEIA.
Article Synopsis
- A study aimed to assess the effectiveness of using phone calls to follow up with patients who had been diagnosed with gastric precancerous lesions (GPL) but lost to follow-up, in order to reduce gastric cancer (GC) mortality.
- Out of 535 GPL patients, 134 were contacted, but only 36 underwent the recommended endoscopy after facing several challenges in reaching them, including not being able to make contact or patients declining the procedure.
- The results indicated that most patients showed stability in their GPL conditions, though one patient progressed to gastric cancer, highlighting the importance of follow-up for early intervention.
Background: Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), considered as gastric precancerous lesion, is of growing interest and recommended by current guidelines. Our aim was to evaluate the diagnostic performance of a panel of biomarkers (GastroPanel®) for the detection of AG in France, a country of a low gastric cancer (GC) incidence.
Material And Methods: In this prospective, multicenter, cross-sectional study, consecutive patients considered at increased risk of GC and undergoing upper endoscopy with gastric biopsies were included.