[Effect of specific antibodies on the electrophysiological properties of the oocyte membranes in mice].

The influence of polyclonal anti-ovarian and monoclonal antibodies, reacting with cell surface membrane, on the electrical activity of mouse oocytes was studied by the intracellular microelectrode recording. The data obtained suggest that specific antibodies alter permeability and excitability of sexual cells.

[Precancerous importance of chronic cystitis and papilloma of the bladder].

Analyzes the findings of histologic studies of biopsies of a pathologically changed and visually intact bladder mucosa from 334 patients with chronic cystitis with nonproliferative, proliferative, and metaplastic changes (n = 164), papillomas (n = 62), and carcinomas (n = 108). Demonstrates the relationships between these conditions and their evolution over a follow-up of 36-72 months. Outlines the most typical patterns of their development and progress eventuating in noninvasive or various forms of invasive carcinoma.

[Electron microscopy in the diagnosis and prognosis of transitional-cell bladder tumors].

The electron-microscopic analysis of 65 different transitional-cell tumours of the urinary bladder revealed quantitative correlations between the tumour cells belonging to different groups, types and forms of transitional-cell papilloma, transitional-cell carcinoma and undifferentiated carcinoma of the bladder. These correlations are of importance for histogenetic and differential diagnosis of these tumours. The correlation between the changes in cell composition of transitional-cell papilloma or transitional-cell carcinoma and the subsequent clinical course of the disease (prognosis) is determined.

[Leukoplakia of the bladder].

The urinary bladder leukoplakia from 42 patients was studied clinico-morphologically, histochemically and electron microscopically. This precancerous condition is observed in 58,3 cases of chronic cystitis, more frequently in females. Three successive stages of the leukoplakia development under the conditions of the inflammatory process can be distinguished: squamous-cell modulation, squamous-cell metaplasia, squamous-cell metaplasia with keratinization.