Two formulations based on diclofenac sodium salt encapsulated into a chitosan hydrogel were designed and prepared, and their drug release was investigated by combining in vitro results with mathematical modeling. To understand how the pattern of drug encapsulation impacted its release, the formulations were supramolecularly and morphologically characterized by scanning electron microscopy and polarized light microscopy, respectively. The mechanism of diclofenac release was assessed by using a mathematical model based on the multifractal theory of motion.
View Article and Find Full Text PDFIn this paper, a practical application of theoretical developments found in our previous works is explored in relation to atmospheric lidar data. Multifractal structures, previously named "laminar channels", have been identified in atmospheric profiles-these exhibit cellular and self-structuring properties, and are spatially ordered across the atmospheric profile. Furthermore, these structures have been connected to the spontaneous emergence of turbulent behavior in the calm atmospheric flow.
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