[Immediate and early results of combined treatment of colonic cancer using neoadjuvant selective intra-arterial polychemotherapy].

The combined treatment of 53 patients with colonic cancer, using neoadjuvant intraarterial polychemotherapy (IAPCT), was conducted. The trustworthy lowering of the catheterized artery thrombosis occurrence rate, the tumor recurrence-by 7%, distant metastases-by 13.9%, two-year survival increase-by 15.

[The use of neoadjuvant selective intra-arterial polychemotherapy and its modifier verapamil in the combined treatment of colorectal cancer].

After combined treatment of 74 patients for colorectal cancer using preoperative neoadjuvant intraarterial selective polychemotherapy (IAPCT) three-year survival index have constituted (77.0 +/- 5.2)%, the cancer recurrence have occurred in (10.

[The use of neoadjuvant intra-arterial polychemotherapy in the treatment of cancer of the genitalia].

Results are submitted of employment of intraarterial superselective polychemotherapy in the treatment of malignant tumors of female genital organs in 106 patients; of these, forty individuals presented with carcinoma of the neck of the womb, 33 with tumours of the trophoblast, 18 had carcinoma of the ovaries, and 15 carcinoma of the body of the womb. A clinical analysis was done of the results obtained as were clinical-morphological correspondences (there has been studied a therapeutic pathomorphosis of the tumours) depending on the disease stage, individual schemes of polychemotherapy. The greatest benefit from the above treatment occurred in proliferative and invasive vascular mole and choriocarcinoma; patients with carcinoma of the neck and body of the womb derived less benefit, those with carcinoma of the ovaries experienced the least therapeutic effect.

[The immediate results of the combined treatment of rectal cancer using intra-arterial selective polychemotherapy].

The treatment experience of 127 patients with the locally spread rectal cancer was summarized. The combined with preoperative intraarterial chemotherapy course application causes significant injurious effect on the tumor (more than 3 times decrease of the viable tumor tissue part by volume in rectal adenocarcinoma, the appearance of subcapsular necrosis regions in metastatically injured regional lymphatic nodes in 32.2% of observations) and is characterized by low common toxicity.

[Effectiveness of transthoracic puncture in the diagnosis and treatment of neoplasms of chest organs].

A complex examination of 1400 patients with pathologies of the lungs and mediastinum was carried out using roentgenologic, endoscopic, bioptic and cytologic methods. Diagnosis was confirmed morphologically in 93.7% of cases.

[Preoperative selective intra-arterial chemotherapy in gastric cancer].

Preoperative intraarterial chemotherapy was administered to 69 patients with gastric cancer. In 34 patients the tumor was localized in the antral portion, in 27 in the body of the stomach involving the proximal portion, and in 8 total involvement of the stomach was revealed. Left gastric artery was catheterized in 42 patients, right gastric-omental artery in 27.

[Effectiveness of transthoracic puncture in the diagnosis and treatment of lung cancer].

The complex examination of 1400 patients with pathologic masses of the lungs and mediastinal organs with the use of roentgenologic, endoscopic, puncture bioptic and cytologic methods was carried out. Morphologic verification of diagnosis was performed in 93.7% of the patients.

[Chemoembolization of blood vessels in the complex treatment of children with nephroblastoma].

The results of roentgeno-endovascular intervention in nephroblastoma in 31 child are presented. For chemoembolization, suspension of lipiodol and adriamycin was used, for control of the effectiveness of the intervention--the radiopharmaceutical preparation pyrophosphate. After embolization, the decrease in tumor size was noted.

[Preoperative superselective intra-arterial polychemotherapy in the treatment of stomach cancer].

Results of treatment of gastric cancer with using preoperative superselective intraarterial polychemotherapy are described. The method was used in 57 patients with gastric cancer of the III-IV degrees and was followed by radical surgical treatment. The use of chemotherapy and operation resulted in complete destruction of the tumor in 63.

[The gonadotropin, prolactin and sex steroid content of the blood from the inferior cavernous sinuses and the adrenal and ovarian veins of women with Itsenko-Cushing disease].

Results are reported of a study of the content of gonadotropins, prolactin and sex steroids in different regions of the vascular bed in women with Itsenko-Cushing disease. It was found that the content of gonadotropins were similar at all levels of the vascular bed indicating their secretion reduction in the pituitary. At the same time there was an increase of prolactin, testosterone, progesterone and cortisol in the blood of the ovarian, adrenal, peripheral and lower cavernous sinus veins.

[Preoperative superselective intra-arterial polychemotherapy in combined treatment of gastric stomach].

In patients with gastric cancer, depending on location of a tumor, the left gastric or right gastroepiploic artery was catheterized via a puncture of the femoral artery, the course of polychemotherapy with fluorouracil and adriablastin was carried out, then the operative treatment was performed. In 62.4% of the patients, the complete, in 18.

[New method of treating Itsenko-Cushing disease by transvenous destruction of the adrenals].

A new method was developed for therapy of Icenko-Cushing's disease using transcatheter transvenous destruction of the adrenals (TTDA) to replace commonly used adrenalectomy. TTDA was performed by means of venous extravasation of a radiopaque agent (76% verografin solution) and its deposition in the organ parenchyma. TTDA was performed in 57 patients with Icenko-Cushing's disease using 3 tactical approaches including roentgenovascular intervention: bilateral TTDA, unilateral TTDA combined with unilateral adrenalectomy and unilateral TTDA combined with chloditan.

[Radioimmunoassay in the diagnosis of arterial hypertension].

The paper is concerned with the results of a study of the aldosterone concentration and renin activity, the general level of catecholamines and their fractions (epinephrine, norepinephrine and dopamine) in the peripheral blood and blood taken at selective venography from the vena cava inferior, renal and adrenal veins of 108 patients with hypertension, aldosteroma and idiopathic hyperaldosteronism, adrenal and extraadrenal pheochromocytoma, renovascular and renoparenchymatous arterial hypertension. The aldosterone concentration and renin activity were determined with radioimmunoassay, and the general content of catecholamines and their fractions with a radioenzymatic method using standard kits. It has been shown that the radioimmunoassay to determine the aldosterone concentration and renin activity in the blood from the vena cava inferior, renal and adrenal veins makes it possible to resort to differential diagnosis of hypertension, aldosteroma, idiopathic and secondary hyperaldosteronism.

[Diagnosis of adrenal cortex diseases using radioimmunoassay of hormone levels in blood samples from the inferior vena cava and its tributaries].

To diagnose the Icenko-Cushing syndrome and disease, samples of the venous blood were taken from the inferior vena cava, the renal and adrenal veins of 51 patients to determine hydrocortisone and ACTH. Thirty-nine patients showed a tendency to an increase in the basal level of hydrocortisone in the blood from the inferior vena cava and the renal veins and a significant elevation of its concentration by approximately an equal value in the blood from both adrenal veins. The ACTH content in their blood was elevated, all these indicating the presence of primary disorders in the hypothalamus-hypophysis system and the secondary involvement of the adrenal cortex in the pathological process, i.

[Selective testicular venography in non-palpable undescended testes in children].

The selective testicular venography can establish the presence and localization of undescended non-palpable testes in children. The morphofunctional state of non-palpable undescended testes can be estimated on the basis of the data obtained which helps to make a correct choice of the surgical treatment.