[Immune reactivity in workers engaged in cement production].

The authors studied immune state of workers engaged in cement production. Ambivalent changes of immune parameters in apparently healthy workers depict various stages of adaptational protective reactions in body system. The studies support gradual changes in immune system under continued influence of occupational factors.

[Methodical aspects of hygienic safety assessment of polymeric materials in contact with foodstuffs].

It was purposed new technique by capillary gas chromatography (GC) for the low level determination of monomer hexamethylenediamine (HMDA) in food simulants water from polymeric materials in contact with foodstuffs. Hexamethylenediamine, HN2-(CH2)6-NH2, is a monomer used in the manufacture of certain of polyamide plastic materials and articles intended to come into contact with foodstuffs. Compound exhibits all the chemical properties of aliphatic amines, is an irritant, causing dermatitis, can accumulate in the body, the degree of human exposure to HMDA assigned to the 2nd class of hazard - the substance is highly dangerous.

[Experience of the conservative treatment of the gallbladder cholesterosis in children].

Gallbladder cholesterosis (GBC) was described more than 150 years ago, but so far the disease remains unknown. With respect to children's age appear solitary works. The introduction of modern pediatric practice of the intrascopic research methods enabled us to objectively identify the pathological changes in the gallbladder wall.

[Morphological and immunohistochemical studies of palatine tonsillar hypertrophy in children].

The paper presents the results of immunohistochemical and morphometric studies conducted to examine an association of the site, the expression of virus antigens, and the nature of morphological changes in the hypertrophic palatine tonsils in children. The distribution of CD3+ and CD20+ cells was explored in tonsillar tissue. The greatest changes were shown in the epithelium, the antigens of herpex simplex virus being more frequently detected than those of human papillomavirus.

[Modern aspects of diagnostics of chronic chlamydiosis caused by persisting forms of Chlamydia].

Aim: To study the possible hematogenic route of dissemination of Chlamydia trachomatis and to analyze efficacy of methods of pathogen detection in clinical specimens (sera and scraping material).

Materials And Methods: Cultural method, electron microscopy, real-time PCR, immunofluorescent assay.

Results: C.

[Antibiotics produced by Photorhabdus luminescens ZMI, a symbiont of entomopathogenic nematodes].

A novel strain of Photorhabdus luminescens ZMI isolated from nematode larvae Heterorhabditis sp. was shown to produce antibiotic complexes with antibacterial and antifungal activities. The antibiotic complexes secreted extracellularly and intracellularly were separated into individual components.

[The hypolipidemic action of the complex emulgator-stabilizer on the basis of laminal and a water extract from roots of alien Saponaria officinalis L. in experiment on the rat].

Within the limits of experimental supervision the estimation of hypolipidemic action of the complex emulgator-stabilizer (CES) on the basis of a water extract from roots of strange (alien) Saponaria officinalis L and laminal in the ratio 1:1,5 has been made. The received results allow to recommend the CES as a complex food additive at infringements of lipide exchange, especially connected with development hyper-cholesterinemia.

[Toxicity assessment of the vegetable emulsifier- the aqueous extract from the common soapwort roots].

Within the limits of experimental observation the assessment of acute and subacute safety of an aqueous extract from Acanthophyllum roots with a solids content of 7%, used as an emulsifier has been manufactured by production of emulsion products. Acute toxicity (LD50) AEAR, probed on mice-male; has allowed to refer to an emulsifier to a class of nontoxic substance. The assessmentof subacute toxicity of an extract (injection in a food allowance within 30 days in a recommended dose--5 ml on 100 g of a standard food allowance) was spent on laboratory rats.

[Guidelines to estimating the parameters of oxidative stress upon exposure to man-made environmental factors].

The authors developed new methods for non-invasive diagnosis of the body's antioxidative balance, by using the kinetic characteristics of spontaneous and induced luminol-dependent chemiluminescence of an expirate. Comparative studies revealed a higher risk of diminished antioxidative protection for younger groups of the population; the total negative influence of techogenic effects and unbalanced nutrition is significant. Normalization of an antioxidative process as one of the mechanisms of formation of the body's non-specific resistance was observed in 90% of cases during medicobiological monitoring.

[Syphilis as a chronic systemic infection].

During the last STDs'epidemic in Russia (1994 - 2004) over 2.7 min people have been infected with syphilis. At present the structure of syphilis morbidity is characterized by 37% of latent forms, including 1.

[Hypolipidemic activity of a water extract from roots carline thistle].

In the researches which have been lead on white not purebred rats--mans on model nutritional hyperlipoproteinemia it fixed hypolipidemic activity of a water extract from roots carline thistle with the content of dry solvends of 7% which.

[Antioxidant and microelement status of the organism: present-day diagnostic problems].

The paper presents methodical approaches to non-invasive biological testing, based upon the found correlations between the parameters of the microelement status and the intensity of free radical oxidation processes in human alveolar moisture. The study demonstrates that the ratio of microelements with close chemical properties that display high biological activity and are key environment pollutants plays a prognostic role in the organism homeostasis.

[Hygienic problems of population health maintenance under the extremal conditions of North].

A range of multi-sided studies, carried out in various regions of Far North (Jamalo-Nenets autonomous region, Komi republic, Sakha republic (Yakutia)) have established the leading hygienic risk factors of population health deterioration, including those characteristic of small nationalities of North. The consideration of the obtained data, including regional alimentary status peculiarities, the condition of metabolic processes and antioxidant balance of the organism, allowed establishment of effective approaches to the maintenance of notherners' health. These approaches are based upon the optimization of nutrition as an element of population health control under extremal conditions.

[Occurrence of Helicobacter pylori specific antigens in diseases of gastrointestinal tract].

The results of the immunophoretic analysis of H. pylori antigenic structure are presented. Along with H.

[The search of antioxidants in plant root's extracts of the carline thistle].

The carrying out tests of water-extracts of carline thistle (plant pink, Caryophyllaceae) in Kazakhstan (extract 1) and gathered in the Primorye region (extract 2). The method of spectral and thin layer chromatography silicagel plates contain phenolys components. It is found out that both extracts contain the same bonds with the max, uptake of long waves lambda = 282 hm and lambda = 260 hm.

[Susceptibility of archaea to the antibiotic effect of the parasporal inclusion proteins from Bacillus thuringiensis subspecies].

The proteins of parasporal inclusions from three Bacillus thuringiensis subspecies (kurstaki, amagiensis, and monterrey) inhibited growth of methanogenic archaea of two species belonging to two genera, Methanobrevibacter arboriphilus and Methanosarcina barkeri. The minimal inhibitory concentrations of these proteins were 20 to 50 micrograms/ml. Lysozyme exhibited similar bactericidal effect on archaea.

[Methodological aspects of gas-mercury monitoring of non-industrial areas].

The paper presents new methodological approaches to gaseous mercury monitoring whose key link is to record the territorial background level of air pollution, which is calculated by using the frequency distribution diagrams of single measurements for uniform objects within an area by comparing them with logarithmically normal random distribution. The methodological approach has been used during surveys of schools and preschool children establishments in Moscow, Kaluga, and the Kaluga Region.

[Effect of amyxin--a domestic analog of tilorone--on characteristics of interferon and immune status of man].

The influence of amyxin, the Russian oral analog of tilorone, on the human interferon and immune status has been evaluated. As revealed by this investigation the administration of amyxin has produced a rise in the content of serum interferon, an increase in the capacity of leukocytes and lymphocytes for synthesizing alpha- and gamma-interferon, the activation of NK and phagocytizing cells of peripheral blood. No essential influence of amyxin on the amount of B and T lymphocytes, their subpopulations and the levels of the main classes of immunoglobulins has been established.

[Medical and biological problems of relationship between food product quality and free radical oxidation state in humans].

Relation between quality of nutrition products and condition not infectious morbidity of the population of Republic Adygea, connected with development of free-radical processes are shown. The levels of contamination of products by nitrates, pesticides, heavy metals are investigated, the contents of vitamins-antioxidants is established. Was applied biotesting fats with use test-culture T.

[Cell biology and life cycle of the testate amoeba Corythion delamarei].

Corythion delamarei Bonnet, Thomas, 1960, a typical testate amoeba with hyaline, filiform pseudopodia (Filosea Leidy, 1879), is a mass and widely spread species in the forest soil of Leningrad district. This species has been studied in natural and experimental conditions by means of morphological, cytochemical and morphometrical methods, including original culturing in vitro. The complex life cycle of C.