[The regional aspects of social economic factors effect on morphophysiological status and somatic health of young women].

The analysis of various social, economic, and demographic factors demonstrates different degrees and directions of their impact on human body systems and human health in general. The examination of residents of several cities of Russia and neighboring countries provides an opportunity to assess strength and direction of relationship between socioeconomic factors and morphofunctional health. The comprehensive morphofunctional examination was applied to 722 young females aged 18.

[Effect of vitamin beverages on vitamin sufficiency of the workers of Pskov Hydroelectric Power-Plant].

The research of influence of vitamin complexes in the form of a drink or kissel on vitamin sufficiency of working persons has been carried out. Long inclusion (6,5 months) in a diet of vitamin drinks containing about 80% from recommended daily consumption of vitamins, was accompanied by trustworthy improvement of vitamins C and B6 sufficiency and prevention of seasonal deterioration of beta-carotene status. As initially surveyed have been well provided with vitamins A and E, their blood serum level increase had not occurred.

[Characteristics of serum lipids and vascular platelet hemostasis in medical staff with arterial hypertension].

Vascular complications of arterial hypertension are known to depend not only on the hypertension level, but also on risk factors including also dyslipoproteinemia and disorders of vascular and platelet hemostasis. Therefore studies of early mechanisms underlying arterial hypertension in medical staffers are topical and serve as a basis for early prevention of cardiovascular complications.

[Involvement of striatal serotonin in fluoxetine effects on adrenocortical function and behaviour].

Treatment of the adult rats with selective serotonin (5-HT) reuptake inhibitor: fluoxetine and its complexes with glycyrrizhinic acid during 2 weeks (25 mg/kg/day) significantly increased plasma corticosterone levels that were measured after 5-min plus-maze. All the drugs decreased the content of 5-HT and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) in the striatum as well as 5-HT in the hippocampus. There was a significant negative correlation between 5-HT in the striatum and corticosterone levels.

[Effects of fluoxetine on locomotor activity: possible involvement of dopamine].

Plus-maze benavior of adult mail rats was assessed and contents of 5-hydroxyindoleacetic acid (5-HIAA) and dopamine (DA) in different brain regions were analyzed after two-week fluoxetine treatment (25 mg/kg/day, per os). Chronic fluoxetine treatment produced a general decrease in the brain 5-HIAA content and a decrease in DA content in the frontal cortex and striatum. Behaviorally, fluoxetine-treated animals displayed enhanced anxiety and decreased locomotor activity.

[Effects of fluoxetine and its complexes with glycyrrizhinic acid on behavior and brain monoamine levels in rats].

Effects of serotonin uptake inhibitor fluoxetine (F) and it's complexes with glycyrrizhinic acid (GA) in molar proportions 1GA : 1F (FGA-1) and 4GA : 1F (FGA-4) on rat behavior in elevated plus-maze and brain monoamine concentrations were studied. Drugs (25 mg/kg) were administered per os 1 h before investigations. F-treated rats showed increased anxiety and reduced locomotor activity, whereas FGA-1 and FGA-4 had no effects on the behaviors.