[Use of itopride in the symptoms of functional dyspepsia in Russia: results of a phase IV prospective open-label multicenter clinical trial].

Aim: To evaluate the efficacy and safety of itopride used to treat the symptoms of functional dyspepsia (FD) of the upper gastrointestinal tract.

Subjects And Methods: A prospective, open-label, multicenter trial using as a control the placebo response obtained in the previous investigations enrolled 96 adult patients. The diagnosis of FD corresponded to its Rome II criteria.

[Gastroesophageal reflux disease model].

The model of gastroesophageal reflux disease by administration of 0.2-0.25 ml of a 1% solution of methylene blue to fundal division of rat stomach was created.

[Idiopathic pancreatitis].

The basic current information on etiopathogenesis, diagnosis and treatment of patients with idiopathic pancreatitis.

[Biliary pancreatitis].

It is provided the basic information of the etiopathogenesis, diagnosis of biliary pancreatitis, drug treatment of patients with holetsistolitiaz, and the information of biliary pancreatitis's prevention.

[Calculous pancreatitis].

Was shown current information on the diagnosis of pancreatic stones, their role in the development of calcificated (calculous) pancreatitis, as well as information on treatment of patients.

[Study of the esophagus and stomach acidification (according to the interpretation of 24-hour pH monitoring data)].

Is demonstrated current information about the nature and method of computing the 24-hour pH-metria of the esophagus and stomach, as well as the Interpretation acidification (acidification) of the gastrointestinal tract.

[Pharmacoeconomic analysis of treatment of certain diseases of the digestive system].

The article provides data of the pharmacoeconomic analysis (cost/effectiveness) of treatment of peptic ulcer, ulcerative colitis, Crohn's disease, gastroesophageal reflux disease, biliary sludge and cholelithiasis. It was shown that the most appropriate treatment scheme is one that characterized by lower costs per unit of effectiveness. Analysis of cost/effectiveness can give an economic assessment of clinical efficacy, compare alternative treatments and help to choose the method by which the efficiency increases faster than the level of costs.

[Results of a multicenter trial "Epidemiology of Gastroesophageal Reflux Disease in Russia" (MEGRE)].

Aim: To assess prevalence of gastroesophageal reflux disease (GERD) in Russia in MEGRE trial in 6 cities of the Russian Federatiion (Kazan, Kemerovo, Krasnoyarsk, Ryazan, St-Petersburg, Saransk).

Material And Methods: Mayo Clinic questionnaire (USA) adapted for Russia was used to question 7812 people over 18 years of age from of random population sample. The symptoms (heartburn and regurgitation) were classified as frequent if they arose once a week and more often for the last 12 months, rare symptoms arose less often than once a week.

[Chronic pancreatitis and enzyme drugs: questions and answers].

The article presents current information on a key aspects of chronic pancreatitis and enzyme drugs in the form of questions posed by physicians at the end of the lectures on topical issues of chronic pancreatitis, and responses to them.

[Autoimmune pancreatitis: diagnostics and treatment].

The article presents current information about the different options for pathological changes detected in patients with autoimmune pancreatitis, the results of clinical, laboratory and instrumental examination of patients, as well as the possibility of drug treatment of patients.

[Decreasing prevalence and incidence of ulcerative disease--an amazing phenomenon of the end of XX and the beginning of the XXI century].

There demonstrated information on reducing the prevalence and incidence of peptic ulcer in the past 10 years in Moscow, as well as the authors' observations about the possible factors underlying the development trend in reducing the incidence and morbidity of peptic disease.

[Standards of diagnostics and drug therapy of patients with chronic pancreatitis. Moscow agreement, 4 March 2009].

IX Congress of the Scientific Society gastroenterologists Russia and XXXV session of the Central Scientific Research Institute of Gastroenterology was held on 2-5 of March 2009 in Moscow. At the joint meeting were taken standards of "diagnostic and pharmaceutical therapy of chronic pancreatitis".

[Multicentre study "Epidemiology of gastroesophageal reflux disease in Russia"(MEGRE): first results].

We aimed to determine the prevalence and clinical spectrum of GERD in the urban population of 6 cities in different parts of Russia (St. Petersburg, Ryazan, Kazan, Kemerovo, Krasnoyarsk and Saransk). A previously validated reflux questionnaire developed at the Mayo Clinic was translated into Russian, culturally adapted and administered.

[Prevalence of gastroesophageal reflux disease in Moscow: results of a population study].

Aim: To study prevalence of the principal symptoms of gastroesophageal reflux disease (GERD) in Moscow.

Material And Methods: A total of 1065 respondents aged 15-85 years (a random representative sample of population of one of the typical Moscow districts) participated in a questionnaire survey using the international questionnaire for detection of GERD incidence.

Results: Epigastric burning (EB) occurs in 39.

[Cholelithiasis and biliary pancreatitis: pathogenetic and clinical aspects].

The main pathogenetic and clinical aspects of the cholecystolithiasis and biliary pancreatitis beginning and progress are discussed, including the results of our investigations.

[Whether enzymatic and antisecretory drugs always correctly used in therapy of the chronic pancreatitis? An information for reflection].

Central scientific research institute of gastroenterology, Moscow It is presented debatable data of expediency of application of fermental medicines in therapies of chronic pancreatitis.