Publications by authors named "Iu V Suvorova"

Effectiveness and safety of regional chemoinfusion in combination with radiation therapy in patients with breast cancer with metastases to the brain was clinically assessed. Cerebral angiography with chemoinfusion was fulfilled in six patients. The procedure could not be fulfilled completely in one patient because of transient vascular and neurological disorders.

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From 1995 to 2006 we performed embolisation in 9 patients with bilateral kidney cancer. Embolization of kidney with smallest cancer was done at the first stage with subsequent embolisation of tumor in the contralateral kidney. Technically all procedures were successful and were performed without complications.

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Embolization of the renal artery was performed as a palliative measure in 93 inoperable patients at the Center's Clinic in 1991-2000. Radio-endovascular intervention was indicated in cases of bleeding (19, 20.5%), case-history macrohematuria with high risk of relapse (54, 58%) and drug-controlled pain (20, 21.

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We evaluated the role of intra-arterial chemotherapy and/or chemoembolization, intravenous systemic chemotherapy and radiotherapy in combined treatment for locally advanced unresectable carcinoma of the head and neck. Transfemoral approach for catheterization with chemoinfusion/chemoembolization of the external carotid artery branches with carboplatin (300 mg/m2), 5-fluorouracil (1000 mg/m2) and gelatin sponge was attempted in 25 patients. Out of that number, 18 received additional radiotherapy.

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Neoadjuvant intra-arterial oil chemoembolization and adjuvant selective intra-arterial chemoinfusion with gemicitabine was administered to 28 patients with operable exocrine pancreatic cancer. It was well tolerated and not followed by complications which allowed for gastropancreatoduodenal resection to be carried out in all cases. Complete course of combined treatment was given to 23 out of 28 patients (82.

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The data are presented on treatment of 131 patients with transitional cell carcinoma of the urinary bladder. Radiotherapy was received by 57, regional intraarterial chemotherapy (RIAT)--27. Radiotherapy was combined with RIAT and selective hyperglycemia (HG) in 18 cases.

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The paper discusses the methods of complex treatment for invasive bladder cancer which includes radiation therapy, regional intraarterial chemotherapy with cisplatin drugs, selective hyperglycemia and local SHF-hyperthermia. Complete local response was reported in 18 (56%) out of 32 patients with stage II-IV tumors, partial--8 (25%), no response--6 (19%). The method appeared effective and safe; it offers good perspectives in bladder cancer treatment.

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The range and frequency of aberrant hepatic arterial anatomies and their significance for placement of implantable hepatic arterial infusion devices have been studied. The angiographs of 1439 patients treated at the Institute's Clinic (1985-2002) were used. The following 6 types of aberrant hepatic arterial anatomy were identified (J.

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A newly developed polysiloxan material for arterial embolization of parenchymatous organs is described. This new agent can be used for distal-proximal embolization with following local hyperthermia. The preliminary results of clinical use are presented.

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We evaluated effectiveness of transcatheter embolization for control of bleeding complicating bladder and uterine neoplasms in 60 patients. Post embolization, bleeding was completely controlled in 95% patients. Complications occurred in 5% of cases.

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The authors made a clinical evaluation of the efficiency of regional bolus chemotherapy and embolization as a stage of combined therapy in patients with inoperable cancer of the tongue and maxilla complicated by bleeding episodes. Carotid angiography by attempting to make chemoembolization was performed in 15 patients. The procedure could not be done in full in 2 (13%) patients due to transient vascular and neurological disorders.

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Collateral circulation in renal tumor was measured at control angiography 2-22 months after therapeutic embolisation in 32 patients with inoperable cancer of the kidney. Collateral circulation was absent in 38% of patients. 20 patients (62%) had 36 collaterals.

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The outcomes of treatment with intravascular embolization/chemoembolization and regional chemotherapy were analyzed in 862 patients with tumors of the kidney (n = 568), urinary bladder (n = 232) and prostate (n = 62). In renal cancer, the five-year survival rates after mechanical embolization followed by nephrectomy were 51%, those after chemoembolization and surgery, 77%. In inoperable cases, they were 3 and 25%, respectively (p < 0.

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