[Protective activity of 28-kDa 1-Cys peroxiredoxin determines its peroxidase activity].

The 28 kDa peroxiredoxin from rat exhibited peroxidase activity only in the presence of dithiothreitol. Both organic and nonorganic peroxidases were found to be substrates for the 28-kDa peroxiredoxin activity. Analysis of the protective antioxidant activity of the 28-kDa peroxiredoxin revealed that it is accounted for by its peroxidase activity.

[Properties of the catalytic center of a secretory 28kDa protein (1-cys peroxiredoxin) from rat olfactory epithelium].

The secretory 28 kD protein, an abundant water-soluble protein from rat olfactory epithelium, belongs to the 1-Cys subfamily of thiol-specific antioxidants (peroxiredoxins). The 28 kD protein contains a single cysteine residue at the position 46 which accounts for the antioxidant activity. Here we studied the effects of N-ethyilmaleimide and t-butyl hydroperoxide on the antioxidant activity of the 28 kD protein and that of the 23 kD protein from rat erythrocyte which is a member of 2-Cys subfamily of peroxiredoxines.

[The effect of ethanol on the food behavior of the snail Achatina fulica].

The feeding behaviour of the land snails Achatina fulica was used for investigation of the effects of different doses of ethanol. The time from the beginning of food (carrot) exposure till the removal of the carrot from the needle was measured. Regression analysis revealed the opportunity of approximation with exponential mathematical model of feeding behaviour time progressive decrease during food exposure.

[Effect of acute alcoholic intoxication on the antigenic composition of soluble proteins in the rat brain].

Cross immunoelectrophoresis was used to study antigenic composition of the brain of rats preferring water, or 15% ethanol and of intermediate group animals. The rat brain showed 6 antigens, one of them was found to be neurospecific. The intermediate group animals and those preferring ethanol differed from those preferring water in that they demonstrated two antigens which were found to be neuro-nonspecific.