[The specificity in promoter recognition by the Bacillus subtilis RNA polymerase deltaA and deltaH holoenzymes is connected with periodicities in the promoter nucleotide sequences].

Promoters recognized by deltaA-RNA and deltaH-RNA polymerase have different periodic patterns their nucleotide disposition. By using the special method of Fourier analysis for symbolic sequences. Fourier spectra of the primary structure of promoters transcribed bv deltaA-RNA and deltaH-RNA polymerase were obtained.

[Analysis of side group conformations in molecular mechanics. Possibility of reduction of the side group conformation library in alpha-helical proteins].

A new reduced library of side-chain conformations in proteins has been formed with the aim to apply it as a start point in the molecular mechanics calculations. The adequacy of this library was demonstrated by computation of X-ray determined a-helical protein (PDB code 1BB1) as example.

[Computation of the structure of collagen molecule fragments].

Step-by-step computations of octapeptide structures was performed for human collagens I and III. It was shown that computational results (coordinates of atoms) practically coincide with X-ray data for the collagen fragment.

[Structure of collagen with a new net of hydrogen bonds].

A conformational variability of the collagen triple helix was studied with the methods of molecular mechanics. The Rich-Crick model with one hydrogen bond per tripeptide fragment or the model with two hydrogen bonds per tripeptide fragment were used for tripeptides forming the primary structure of the protein. Imino acid and amino acid residues were located in the second position of the tripeptide fragments in the first and second cases, respectively.