[Postmortem assessment of labor from changes in the skull and brain in fetuses and newborn infants].

The paper gives data on the ways of identifying the pattern of head insertion, wire point, the degree of head flexion and extension, asynclitism, and configuration from the fetal and neonatal skull. The findings are important for the assessment of the course of labor and the quality of its management and for the diagnosis of birth injury. Emphasis is laid on the significance of brain compression in the genesis of fetal asphyxia.

[The first department of infectious diseases in Russia: history of formation, main achievements and prospects of the national infectology].

Russian first department of infectious diseases, which has great traditions and achievements, as of right is a brilliant constellation of national researchers and practitioners military infectology, not only brought the Kirov Military Medical Academy into repute, but also made a huge contribution to the development of the science of infectious diseases and the establishment of an effective system treatment and prevention of these diseases. This article outlines the main historical stages of infectology in the armed forces of our country, summed up the contribution of members of the Department of Infectious Diseases of the Military Medical Academy in medical science, marked modern progress and prospects of development of military infectology.

[Clinical and epidemiological value of adenovirus infection in the military personnel].

Adenovirus infections occur in different military groups as acute respiratory diseases combined with backsets and pneumonia. At definition of etiological structure of acute respiratory diseases in 1606 soldiers of 1-2 year of service, placed in the division of infectious diseases of the military medical academy in 2000-2011, dominance of an adenoviral infection (37.4%) was revealed, especially in non-epidemic periods of influenza (77% in 2007-2008).

[HIV-infection as a risk factor of professional contamination of the military medical hospital personnel].

In Military-medical academy named by Kirov S.M., 857 HIV-infectioned patients were treated.

[Comparative clinical and epidemiologic characteristic of HIV infection in women from discordant pairs].

Forty HIV-positive women living with HIV-infected sexual partner as well as 40 HIV-positive women from discordant pairs (HIV-positive wife and HIV-negative husband) were surveyed. Less than half of HIV-infected patients (40%) specified the use of condoms for sexual contacts. In the group of women living with HIV-infected partner more expressed immunosupression (CD4 count 427 cells/mcl versus 528 cells/mcl) was observed.

[Immunopathogenesis of viral hepatitis C. Immunological markers of the disease progression].

Results of studies of immune response during hepatitis C virus (HCV) infection were reviewed in order to reveal immunologic markers of the disease progression. Genetic heterogeneity of HCV and immunogenetic features of the host determine heterogeneity of immune response to the virus and differences in the course of the disease and outcomes. Spontaneous elimination of HCV-infection in acute phase occurs due to vigorous and sustained multispecific Th1-response toviral antigens.

[Motor activity of infusoria: fundamental and applied aspects].

The article considers morpho-functional organization of the cilia, locomotor organelle of the infusoria, and demonstrates the complicity of locomotor behavior of these protista. The problem of control of locomotion of infusoria is whole organism in discussed; and conclusion is drawn that system of control of movements could be multilevel and include receptor, afferent, central, efferent and effector units. In this context the macronucleus, could act as a central integrator and coordinator of the locomotor behavior being closely connected with periphery by dynamic elements of cytoskeleton.

[Effect of respiratory infections on the clinical course of coronary artery disease].

The subjects of the study were 64 patients with coronary artery disease (CAD), and 38 healthy controls. The study included determination of Chlamydia pneumonia (CLPN), Toxoplasma gondii (TG), Herpes simplex virus (HSV) 1, 2, Epstein-Barr virus (EBV), and antibodies to these microorganisms. Diagnostically significant elevation of the serum levels of IgG antibodies to CLPN, HSV 1, 2, or TG was associated with CAD progression, and seropositivity to several of the agents strongly correlated with CAD progression.

[Modern medical science and Military Medical Academy].

The article presents the information about the main directions of scientific investigations of Military Medical Academy and their results during the period of 1999-2000. The scientific work was conducted in conformity with demands of orders and directives of RF Ministry of Defense. 12 integrated scientific problems were formed in the annual plans of the Academy's research work.

[The automatization of the control over the processes determining the risk of HIV-infection spreading among servicemen].

The possibilities of the control over the processes determining the HIV-infection spreading risk are considered. In the view of that the automated system which enables to evaluate risk factors predetermining the appearance of new infection cases was proposed. These factors are systematised in a multilevel database.

[The condition of the stomach, duodenum and bile ducts in patients with chronic hepatitis C].

Aim: To study the status of the stomach, duodenum and biliary tracts in young patients with chronic hepatitis C.

Material And Methods: We studied associated pathology of the gastroduodenal zone and biliary tract in 140 patients with CHC aged 16 to 35 years (mean age 25 +/- 0.8 years).

[Comorbid gastric and duodenal changes in chronic hepatitis C in young patients].

Characteristics of the gastroduodenal zone, frequency of gastric mucosa contamination with Helicobacter pylori (HP) were studied in young patients with chronic hepatitis C (CHC). Affections of the stomach and the duodenum were encountered in 76.3% of CHC patients.

[Clinical and laboratory features of severe forms of acute viral hepatitis B].

Aim: To establish the clinical and laboratory features of severe forms of acute viral hepatitis B (AVHB).

Materials And Methods: 141 patients (88 males and 53 females) with different forms of the disease were examined. Among them there were 30, 33, and 78 patients with mild, moderate, and severe AVHB, respectively.

[Cardiopathy in infectious diseases: clinical and pathogenetic aspects of diagnosis].

The disease of cardiovascular system is one of the causes of invalidity and unfavorable outcomes. Together with such common diseases as rheumatism, hypertension, atherosclerosis that cause the development of cardiovascular insufficiency there are many other diseases including the infectious one that have rather unfavorable influence on the myocardium and vascular system. The disorders in cardiovascular functions at acute infectious diseases are noted frequently (80%) and closely connected with total pathogenesis of the disease.

[Perfluorocarbonic compounds application as a new approach in pathogenic treatment of severe forms of viral hepatitis].

Perfluorocarbonic blood substitute Perftoran (PF) was used in combined intensive therapy of 79 patients with severe viral hepatitis B as a polyfunctional pathogenetic drug according to the following scheme: intravenously 400 ml 1-2 times a day for 2-6 days (800-2400 ml per course). PF exhibited immunomodulating, antioxidant, membrane-stabilizing and disintoxicating properties. The immunomodulating effect of the drug manifested itself in its influence on functional activity of macrophages, reduction of their oversection of proinflammatory cytokines: IL-1 beta, IL-6, IL-8, TNF-alpha.