[Dental and oncological status of patients with tongue carcinoma].

After the supervision over patients with cancer of mucous membrane of oral cavity (MMOC) admitted for treatment in the Tver Regional Clinical Oncological Hospital (TRCOH), the analysis of 427 primary revealed cases of cancer of mobile part of the tongue MPoT (S 02) was carried out. The study included retrospective analysis of case records of 237 patients treated from 1997 to 2013 with the diagnosis of MPoT and prospective examination of 190 patients treated by authors in specialized departments of TRCOH. On the basis of questioning of 67 III-IV stages tongue carcinoma patients at the age of 50-59 years clinical course features, cancer risk factors and oral care patterns were studied.

[Role of selective decontamination in combined treatment of chronic anal fissure].

Effectiveness of selective decontamination in combined treatment of patients with chronic anal fissure and concomitant proctitis was studied in clinical randomized investigation including 103 patients. The etiologically significant flora colonizing the chronic defect of the anoderma does not coincide with the composition of feces microflora and is presented by anaerobic microorganisms or a combination of aerobes and anaerobes. It was established that topical etiotropic antibacterial therapy in combination with medicamentous sphincterotomy in the outpatient treatment resulted in quicker arrest of the pain syndrome, accelerated epithelization of the fissure and made the period of treatment 2 times shorter as compared with control.

[Clinical evaluation of prevalence of seborrheic keratosis of face and neck skin among oncological patients].

Clinical resuls of examination of 280 oncologic patients 51-60 are presented. The aim was to detect seborrheal keratosis of face and neck in these patients. 280 patient of given age group of maxillo-facial department were controls.

[Effects of short-term immunosuppression on the engraftment of skin transplants at syndrome of the diabetic foot].

Effects of a single administration of small doses of 5-fluorouracil on results of skin plasty for syndrome of the diabetic foot were studied in 61 patients who had undergone local operations for pyo-necrotic diseases of the foot against the background of diabetes mellitus. The completion phase of their treatment was free dermal plasty with a split skin graft. Administration of 5-fluorouracil during the plasty operation was found to be accompanied by less marked inflammatory reaction in the transplant bed and in the graft.

[Method for improving results of local operations for pyo-necrotic disease of the foot associated with diabetes mellitus].

Under study was the influence of antimetabolite 5-fluoracil with the preferential influence on the lymphocytic link upon the outcomes of local operations in patients with diabetic foot syndrome. The investigation was performed in 95 diabetes mellitus patients who had undergone local operations for pyo-necrotic diseases of the foot. The group of investigation included 55 patients additionally given 5-fluoracil (5 mg/kg) during local operation.

[Reactivity of neutrophils in systems with peptidoglycans of different species of Staphylococcus].

The work presents the results of the comparative study of the luminol-dependent chemiluminescence of human neutrophils stimulated with peptidoglycans of 14 staphylococcal species. The intensity of chemiluminescence greatly varied, which was not linked with specific antigenic and structural features of peptidoglycans. The maximal chemiluminescence was induced by S.