[Development of polycomponent metabolite probiotic].

Aim: Construct composition of polycomponent probiotic based on lactobacilli cultural fluid (CF) supernatant.

Materials And Methods: Species membership of lactobacilli strains was specified by analysis of nucleotide sequences of 16S RNA genes. For comparison of probiotic effect of CF, supernatant and ultrafiltrate of a consortium of lactobacilli strains, studies of specter of peptides, amino- and other organic acids contained in them as well as profile of bactericidal and fungicidal activity was carried out.