[Evaluation of intestinal viability on a simulation model of a small ileus based on determination of dielectric parameters].

Interrelationship between dielectric parameters and level of ATPH before and during ischemia, as well as with indices of survival after elimination of strangulation, was estimated on a simulation model of strangulation ileus in rats. The data obtained permit to suppose, that parameter tg δm may be used as effective noninvasive criterion of diagnosis in real time for estimation of the intestinal wall state in strangulation. Resection of the infringed intestine without elimination of strangulation is necessary in tg δm less than 2.

[Impact of abdominal cavity open EHF irradiation on activity of adhesive process in peritonitis].

In experiment on 45 rats a purulent peritonitis was simulated. There was established, that on background of a standard therapy for peritonitis application of abdominal cavity open irradiation of extreme high frequency (EHF) have promoted rapid stabilization of the lipid metabolism indices and the blood coagulation system, the reduction of intensity of lipids peroxidal oxidation processes and severity of systemic inflammatory reaction. Under the influence of complex treatment the severity of adhesive process was reduced in 5.

[Intraabdominal hypertension syndrome in patients with abdominal sepsis].

Investigations were conducted in 53 patients, operated on in 2013 yr for abdominal sepsis (AS). The patients state severity was determined in accordance to the systemic inflammatory reaction and the polyorgan insufficiency severity. In 28 patients (group I) AS was diagnosed, in 14 (group II)--severe AS, in 11 (group III)--a septic shock.

[Enhancing efficacy of the primary antibacterial therapy for intraabdominal infections].

The positive experience of their own for combined application of Hepacef and Ornizol preparations (manufactured by firm ARTERI-UM, Ukraine) as an empirical antibacterial therapy for intraabdominal infections was summarized. The preparations efficacy, the disease outcome and possible recommendations for their application in the intraabdominal infection treatment were estimated.

[The features of sclerotic development in junction-ureteral segment of children with congenital hydronephrosis].

A comprehensive clinical, laboratory, instrumental and morphological study of children with congenital hydronephrosis has been carried out. We compared the clinical features of pyelonephritis at children with primary pyelonephritis and congenital hydronephrosis. Bacterial inflammation was dominated symptom at the children with primary bacterial pyelonephritis, whereas children with hydronephrosis had low-grade clinical changes and significant renal functional impairment.

[Comparative estimation of the application efficacy for ceftriaxon and Hepacef combi preparations in the abdominal infection treatment].

A positive experience was described in the work, concerning application of Hepacef combi (cefoperazon/sulbactam, manufactured by "ARTERIUM" (Corporation, Ukraine) in the treatment of inflammatory-purulent diseases of abdominal organs as a method of empirical therapy. There was the preparation action efficacy estimated together with the diseases outcomes analysis, and possible recommendations for its application suggested. The preparation may be recommended for application as the empirical therapy agent in the abdominal infection treatment.

[The change of some indices of coagulogram in rats in experimental pancreonecrosis under the influence of electromagnet irradiation of extremely high frequencies].

The dynamics of changes of some coagulogram indices under the influence of electromagnet irradiation of extremely high frequencies was studied in rats in conditions of experimental pancreonecrosis. Irradiation of abdominal cavity in animals, using electromagnet irradiation with the 6.5 mm wave length, reduces hypercoagulation shifts essentially and raises the plasm anticoagulant and fibrinolytic activity.

[Investigation of anti-inflammatory action of electromagnetic irradiation of extremely high frequencies in experiment].

There were studied some mechanisms of the effect realization of the extremely high frequency electromagnet irradiation, including modification of the organism immune status as an answer on the irradiation action, manifested by mobilization of ripe CD4+ and CD8+ T-lymphocytes, the interleukins (IL) concentration enhancement, including, IL-1, IL-10, as well as the levels lowering of IL-6 and C-reactive protein in the blood serum. There was established, that using a switching on the intermediate signal systems it is possible to induce the directed (antiinflammatory) answer of organism towards the effective parameters of electromagnet irradiation.

[Antibacterial therapy of severe intra-abdominal infections].

The experience of meropenem (Mepenam, manufactured by Corporation ARTERIUM, Ukraine) application as empirical therapy in severe intraabdominal infections was presented. The diseases outcome and the preparation efficacy were estimated, recommendations concerning its application in the treatment of severe intraabdominal infections were done.

[Preclinical diagnostics and correction of the disturbed renal blood flow in the children presenting with diabetic nephropathy].

The present study included 86 children aged between 7 and 17 years with type 1 diabetes mellitus from 1 to 15 years in duration. In all the patients, renal blood flow was investigated with the use of ultrasonic dopplerography. The results of the study suggest disturbances of intrarenal hemodynamics that manifested themselves as enhanced resistance of renal arteries from periphery to the centre in the patients at the hyperfiltration stage of diabetic nephropathy (DN) in conjunction with the reduced velocity of blood flow in inter-lobular and segmental arteries.

[Surgical tactics in acute paraproctitis].

Individualized tactics of radical surgical treatment, applied in 100 patients, suffering an acute paraproctitis, was presented. Performing comparative estimation of the treatment results in 110 patients, in whom the conventional surgical approaches were applied, there was established, that an active surgical tactics secures essential reduction of the patients stationary treatment duration, the rate of the disease recurrence occurrence and transformation into the chronic illness.

[Complex treatment of pulmonary abscesses and pleural empyema in patients with severe thoracic trauma].

The results of complex treatment of 40 injured persons with severe thoracic trauma, in whom pulmonary abscesses and pleural empyema had occurred postoperatively, were analyzed. Complex treatment of pulmonary abscesses and pleural empyema, using the methods of a local superhighfrequency irradiation of purulent foci have promoted their accelerated regression occurrence and reduction of a systemic inflammatory reactions severity, as well as prophylaxis of secondary purulent-septic complications, permitting to achieve lethality lowering and to escape practically reoperations performance.

[Application of preparation quadrocef in the treatment of surgical sepsis].

Comparative estimation of the treatment result of severe abdominal infection, using cefalosporins of the fourth generation maxipim and Quadrocef (Arterium, Ukraine) was accomplished. High efficacy of Quadrocef preparation and possibility of its application as a first-line preparation for severe infections was proved.

[Regional vasotropic and hepatotropic therapy in the complex treatment of postoperative purulent peritonitis].

In 8 patients, operated for postoperative spreaded purulent peritonitis, umbilical vein was catheterized, postoperatively angiographic investigation was performed, leaving catheter in tr. coeliacus or a. mesenterica superior, through which regionary hemodilution, using drop infusion of 20 mcg of alprostan during 3-4 days.

[Application of ultra high frequency irradiation in prophylaxis and treatment of complications of infectious pancreonecrosis].

Local super high frequency irradiation was applied in 9 patients, suffering the pancreonecrosis (PN) inflammatory-purulent complications. Introduction of local super high frequency irradiation to the complex of treatment permits to prevent the PN purulent complications occurrence, to improve the immediate results of the patients treatment.

[Comparative characteristic of respiratory pattern responses to kainic acid microinjections in different parts of the nucleus ambiguous].

In rats, local chemical isolation of neurones by the kainic acid helped to investigate into comparative role of different parts of the n. ambiguus in respiratory control mechanisms. We disclosed specific peculiarities of responses of rhythm and respiratory pattern to chemical isolation of different parts of the n.

[The role of the intestine in the pathogenesis of the multi-organ dysfunction syndrome in diffuse peritonitis].

Extraction of oxygen (O2), ultrastructural organization of intestinal macrophages and translocation of microorganisms were studied on 50 male rats of Wistar line in 2, 6, 12, 24 and 48 hours after the stimulation operation performance (control group) and modelling of an acute purulent peritonitis (APP)--basic group. Increase of common and lowering of intestinal extraction of O2 in early terms of the APP occurrence, accompanied by intensive reproduction of microorganisms and change of intestinal biocenosis, was noted. These infringements correlated with translocation of microorganisms through mesenteric lymphatic nodes--ductus toracicus--systemic blood flow (basic way) in term up to 24 hours and through portal vein--hepar--systemic blood flow (additional way)--up to 48 hours after the APP beginning.

[Functional condition of gallbladder after stomach resection by Roux].

This study examined the results of surgical treatment of 90 patients with ulcerative stenosing disease of the stomach and duodenal ulcer between 1984 and 1995. 30 patients (study group) underwent stomach Roux resection. Truncal vagotomy with stomach Bilroth-I resection (control group) was made in 20 patients, 20 patients had a truncal vagotomy with pyloroplasty according to Heineke-Mikulicz (control group), and 20 patients had a selective proximal vagotomy with gastroduodenostomy by Joboulay (control group).

[A physiological analysis of dissociative learning against a background of physostigmine and pentobarbital].

Physostigmine (0.7-0.8 mg/kg, i.

[Dynamic scintigraphy of the kidneys using lasix].

Dynamic scintigraphy with lasix (urosemide) in 59 patients with hydronephrosis, nephrolithiasis, chronic pyelonephritis, ureterohydronephrosis on an initial scintigram has shown retention of 99mTc-DTPA in the urinary tracts: an increase or absence of the excretory segment on the activity-time curve up to the appearance of an obstructive type of a curve. Verified operative findings in 19 patients with hydronephrosis and nephrolithiasis have shown a high sensitivity and accuracy of the detection of stenosis of the urinary tracts in the absence of the excretory segment on an initial scintigram irrespective of the fact whether it appears or not on a scintigram after lasix administration. Stenosis of the ureteropelvic segment can be observed in the presence of the excretory segment on an initial scintigram with a prolonged half-period of RP excretion; its 2-fold decrease is noted on a scintigram after lasix administration.

[Changes of the functional indices of the liver in patients with phlegmons of the maxillofacial area based on gamma scintigraphic data].

Hepatic functional activity was studied. Liver was considerably enlarged and its functional indices decreased at the early postoperative stages, especially in patients suffering from severe inflammation. These results compared with the clinical indices of intoxication, one can infer on the major role of medium mass molecules in the increased blood toxicity in these patients.