Publications by Iu S Taskaeva

Publications by authors named "Iu S Taskaeva"

Page 1 of 1

Expression of Markers Associated with Epithelial-Mesenchymal Transition and Extracellular Matrix Degradation in Human Uveal Melanoma.

A Yu Shatruk N P Bgatova A V Yeremina A N Trunov V V Chernykh Iu S Taskaeva

Bull Exp Biol Med

October 2024

Article Synopsis

The study analyzed human uveal melanoma tissue samples for markers related to epithelial-mesenchymal transition (EMT) and extracellular matrix (ECM) degradation using immunohistochemical staining.
Increased levels of EMT markers, specifically E-cadherin and vimentin, were found in the tumor tissue, suggesting changes in cell behavior.
The imbalance in MMP-9 versus TIMP-1 proteins indicates heightened ECM degradation, potentially facilitating the invasive growth of uveal melanoma.

View Article and Find Full Text PDF

Comparative Study of Cytotoxicity and Accumulation of Boron and Lithium-Containing Drugs in Skin Melanoma Cells In Vitro.

A I Kasatova I A Razumov S Yu Taskaev Iu S Taskaeva

Bull Exp Biol Med

October 2024

We studied cytotoxicity and accumulation of boron and lithium by cultured human fibroblasts and human and mouse skin melanoma cell cultures. The cytotoxicity of boron and lithium drugs was assessed by MTT tests in the boron and lithium concentration range of 10-640 μg/ml. Cell viability was significantly reduced after incubation with boron and lithium at concentrations >160 μg/ml.

View Article and Find Full Text PDF