[The response of EEG activation in different neurohumoral conditions].

In order to examine under what neurohumoral condition response to the usual opening of the eyes is an incentive for the activation, electroencephalographic, electrocardiographic and electromyographic characteristics of the eyes open reaction in relation to the psychometric indicators of emotional stress and cognitive performance were recorded in 59 healthy women aged 18-27 every 2-3 days for 1-2 menstrual cycles, established in accordance with the morning levels of progesterone. For excluding NOVELTY factor influence one 29 women started monitoring at menstrual phase and other 30--at luteal phase of menstrual cycle. 30 women participated in a one-time monitoring, in which the relationship of these parameters with the current level of progesterone and cortisol in saliva was studied.

[Evaluation of different methods of hemostasis when performing laparoscopic partial nephrectomy].

The experience of performing 44 partial nephrectomies using laparoscopic and lumboscopic approaches is presented. A comparative analysis of the effectiveness of different methods of hemostasis when performing nephron sparing interventions was conducted. It is shown that physical methods of hemostasis do not meet the necessary requirements, increasing warm ischemia time and the risk of intraoperative blood loss, and makes it difficult to visualize the boundaries of resection.

[Comparative effectiveness of fluoroquinolones and beta-lactams in the complex therapy of patients with chronic pyelonephritis].

A comparative study has evaluated the effect of fluoroquinolones and beta-lactams on clinical and biochemical manifestations of chronic pyelonephritis (CPN). 108 patients aged from 18 to 59 years (mean age - 40.26 +/- 10.

[Nutrition mistakes in patients with nonalcoholic fatty liver disease and the ways of correction].

Unlabelled: THE AIM OF REVIEW: To verify the role of nutrition in development of Nonalcoholic Fatty Liver Disease in patients with metabolic syndrome.

Original Positions: The article contains main conceptions of etiology and pathogenesis of Nonalcoholic Fatty Liver Disease. Spesial attention gives to the role of nutrition in development of this case.

[Phase II clinical trial of autologous dendritic cell vaccine with immunologic adjuvant in cutaneous melanoma patients].

This paper describes the clinical results and immunologic changes in cutaneous melanoma patients receiving active specific immunotherapy with autologous dendritic cell vaccine (DCV) in combination with cyclophosphamide used as immunologic adjuvant. Twenty eight patients with morphologically verified stage III-IV cutaneous melanoma receiving therapy in N. N.

[The role of fibrin clot degradation products in the regulation of vital functions of PC-12 cells].

The products of the fibrin clot hydrolysis performed by PC-12 cells modulated dose-dependently the rate of cell proliferation and favored their survival when seeded in suboptimal density. Co-incubation of PC-12 cells with fibrin degradation products enhanced cell adhesion to tissue culture plastic, as well as the number of nicotinic acetylcholine receptor alpha3 and alpha5 subunits expressed. It was demonstrated that, in fact, such a heterogeneous and comprehensive influence was a sum of effects exerted by different fibrin fragments.

[PC-12 cells hydrolyze the fibrin clot by producing both plasminogen and its tissue activator].

It has been shown that rat pheochromocytoma PC-12 cells degraded fibrin clots in vitro. SDS-PAGE performed in the gels of different density and Western blotting using monoclonal antibodies against DD- and D-fibrin fragments demonstrated that both high and low molecular weight degradation products similar to those of fibrin hydrolysis by plasmin had been formed. Enzyme electrophoresis, chromogenic assay and enzyme-linked immunosorbent assay using tPA-specific antibodies demonstrated that PC-12 cells constitutively secreted both plasminogen and tPA.

[Antimicrobial activity of blood phagocytes in patients with tuberculosis and respiratory sarcoidosis].

Examination of 82 patients has revealed that pulmonary tuberculosis is characterized by a considerable increase in the antimicrobial activity of phagocytes: the drastic elevation of the plasma level of neutrophilic elastase and the changes opposite in direction in the phagocytic content of nonenzymatic cation proteins and myeloperoxidase. There is evidence for that the activation of circulating phagocytes is much less pronounced in patients with respiratory sarcoidosis. The significantly less plasma activity of neutrophilic elastase and the significantly greater phagocytic values of cation proteins suggest that the synthesis of secretion products prevails over their degranulation in sarcoidosis.

[Assessment of the dental status, acid-base balance in the oral cavity and Ph of the gastric medium during the use of the Dirol chewing gum].

The goal of our research was to study the short-term and long-term effects of the Dirol chewing gum on the oral cavity state and acid-forming stomach function in patients with hyperchlorhydria. It was revealed that the rational use of this chewing gum by patients with increased gastric secretion can normalize the gastric acidity. Another result of the use of this chewing gum is the improvement of the oral cavity hygienic state and reduced growth of dental caries.

[Complement-binding and immuno-modulating properties of polyreactive immunoglobulins].

New data concerning biological properties of polyreactive immunoglobulins (PRIG) were obtained as a result of treatment of mouse serum immunoglobulins by 4 M KSCN and are presented in the paper. In particular, the capacity of PRIG to bind C1q, the subunit of the first component of complement was studied. It was shown that PRIG's binding capacity to C1q is similar to that of intact immunoglobulins.

[Regulation of fibroblast adhesion by polyreactive antibodies].

The effect of polyreactive antibodies on fibroblast adhesion was studied. Dose-dependent decrease of adhesion was found at the stage of adhesive complex formation. A possible mechanism of this effect was determined as a steric influence on integrin agregation and clastering.

[Mycotic aneurysms of the thoraco-abdominal part of the aorta].

Mycotoc aneurysms (MA)--a rare and extremely dangerous lesion of the aorta. CT, MRA and aortography were used to diagnose MA of the thoracoabdominal areas in 2 men of 64 and 67 years of age. The clinical picture included: fever with shivering with the temperature 38-39 degrees C and increasing pains in the inferiothoracic and lumbar areas of the spine.

[Complex effects of cavinton on climacteric symptoms].

The use of nonhormonal drugs in order to ameliorate climacteric symptoms makes it possible to treat also those women in whom there are some contraindications or lack of compliance for taking hormonal replacement therapy. The drugs with complex effects on the whole body functions are more widely used recently. The aim of the present study is to assess the therapeutic effect of Cavinton (vinpocetin) on the degree of climacteric symptoms and to verify its complex beneficial influence.

[Immunotherapy in the complex treatment of patients with atopic dermatitis with sensitization to house dust mites].

Ninety-nine patients aged 16-52 years with disseminated atopic dermatitis at the remission were examined and treated. The patients were divided into 3 groups according to the method of therapy. Group 1 (28 patients aged 17-52 years, found to be sensitive to Dermatophagoides pteronyssinus and D.

[Allergic sensitivity in different groups of patients with atopic dermatitis].

69 patients with atopic dermatitis, aged 16-42 years, were examined. The patients were divided into two groups: group 1 consisted of patients with atopic dermatitis and bronchial asthma and/or allergic rhinitis (25 patients), group 2 consisted of patients without the respiratory syndrome (44 patients). Scarification skin tests made it possible to find out the essential difference in the sensitivity of the examinees in these two groups.

[Transformation of serum immunoglobulins to polyreactive antibodies].

In order to elucidate the mechanism of induction of serum immunoglobulins polyreactive properties by chaotropic ions, gel-chromatography of immunoglobulins in the medium containing 3.3 M KSCN, has been done. It was found that the transformation of serum immunoglobulins to polyreactive antibodies, which could react with different serological unrelated antigens, was not followed by dissociation of any hypothetical blocking factors.

[Taurine and carnosine in tissues of Pacific mollusks].

The containing of taurine and carnosine (low-molecular biologically active substances) was studied in tissues of molluscs (Gastropodae, Brahiopodae and Cephalopodae) by 38 species. The highest concentration of taurine found in the octopus and 5 species of shells (Gastropodae). The containing of carnosine in mollusks is highly lower than in bovine muscles.

[Ophthalmological symptoms in patients with internal carotid artery pathology].

Ophthalmologic examinations were carried out in 92 patients, mean age 55.4 years, with internal carotid artery abnormalities (stenoses and thromboses) confirmed by dopplerography. Various visual disturbances were diagnosed, the most prevalent ocular symptom being transitory homolateral blindness which was detected in 28 (30.

[Chromatographic analysis and immunobiologic properties of tuberculins].

Immunobiologic activities of tuberculin preparations and their components have been comparatively studied using gel filtration and high-performance liquid chromatography (HPLC) techniques. It is shown that high-molecular weight fraction of protein-purified derivate tuberculin (PPD) had higher activity as compared to nonfractionated preparation in skin tests on guinea pigs sensitized with Mycobacterium bovis BCG as well as in enzyme-linked immunosorbent assay with affinity purified rabbit antibodies against PPD. Using the preparative HPLC-technique we failed to isolate a component of PPD having greater tuberculin test potency than nonfractionated preparation.

[Seasonal changes in the count of mites of the family Pyroglyphidae in houses in the city of Cheboksary].

The results of human dwelling houses surveying for the presence of home dust mites and study of seasonal changes of their quantity in the town of Cheboksary are given. It has been found that the old wooden houses are inhabited by mites, in modern blocks of flats they are met rather seldom. The quantity of alive mites is maximum in September-October.