Publications by authors named "Iu P Mazhara"

The antioxidant effect encountered in laser irradiation of venous blood suggested the study of the possibility of its use for the prevention of the reperfusion syndrome in myocardial infarction (MI). Analysis of biochemical, electrophysiological, hemodynamic, and morphohistological data obtained in experiments on male rats and in clinical cases showed that irradiation of venous blood by the LG-75 helium-neon laser with a wavelength of 632.8 nm produced the best effect.

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Experiments were conducted on Wistar rats to study the effect of laser radiation (LR) with a wavelength of 632.8 and 890.0 nm and power of 0.

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ACTH, hydrocortisone and cyclic nucleotides levels, beta-receptors sensitivity, lipid peroxidation (LPO), antioxidant system, hemodynamics were investigated in 93 coronary patients without myocardial infarction in the presence of cardiac arrhythmia and after its correction. The clinical and laboratory findings indicate that it is primarily LPO activation and LPO products excessive accumulation in the blood that are responsible for arrhythmia emergence. Experimental data support these results by showing possibility of cardiac arrhythmia onset due to LPO products which raise the density of Na-Ca channels and inhibit the activity of Ca-dependent ATPase.

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