[The use of melatonin for correction of sleep disturbances in assembly-line shift workers with arterial hypertension].

Effects of melaxen on the circadian chronostructure of AP and pulse rate was studied in 57 assembly-line shift workers with arterial hypertension of whom 23 were given melaxen with teveten and 34 teveten alone for 3 weeks. Introduction of melaxen in therapy of AH reduced AP and normalized disturbed circadian hemodynamics. Moreover, combined treatment eliminated sleep disturbances not infrequent in such patients.

[Characteristics of circadian rhythms of arterial pressure in patients with hypertensive disease engaged in intense shiftwork activities].

Pathophysiological mechanisms underlying disturbances of circadian rhythms and arterial pressure (AP) were studied in 225 subjects engaged in intense shiftwork activities. Group 1 included 65 persons presenting with borderline arterial hypertension (AH), group 2 69 patients with stage 1 hypertensive disease (HD), group 3 61 patients with stage 2 HD. Control groups was comprised of 30 health volunteers working under similar conditions.

[Evaluation of psychophysiological status and performance ability in patients with hypertensive disease employed under strained working conditions].

The aim of this work was to study psychophysiological functions in HD subjects during strenuous conveyor-belt work. It involved 225 participants of whom 195 presented with different stages of HD. Group 1 (n = 65) included patients with prehypertension, group 2 (n = 69) with stage 1 HD, group 3 (n = 61) with stage II HD.

[The use of melaxen in combined therapy of arterial hypertension in subjects occupied in assembly line production].

The work was designed to study effect of melaxen on circadian chronostructure of arterial pressure and pulse rate in subjects with arterial hypertension occupied in assembly line production. A total of 57 patients were examined of whom 23 received teveten together with melaxen and 34 were treated with teveten alone for 3 weeks. Inclusion of melaxen in combined therapy of hypertension reduced arterial pressure and normalized disturbed circadian hemodynamics.

[Analysis of behavioural and emotional personality characteristics in patients with hypertensive disease and effect of therapeutic education on the quality of life].

The study was designed to assess selected behavioural and psychic personality characteristics in subjects with hypertensive disease engaged in strenuous labour activity and evaluate effect of their self-care education on quality of life. A total of 126 patients were involved in the study of whom 96 were treated and instructed in the framework of the "School of psychophysiological adaptation" program and 30 comprised the control group. They were followed up for 2 years.

[Psychosomatics in patients with hypertensive disease under conditions of occupational stress].

The aim of the work--the investigation of peculiarities of psychosomatic relations in patients with different stages of hypertensive disease (HD) in conditions of direct occupation activity. The 225 workers from a number of large pharmaceutical industries, who was engaged in performance of the basic occupation activities in conditions of conveyor manufacture at the alternating working regimen, that seemed to be an origin of stresses. On grounds of blood pressure level the patients were selected into 3 groups.

[Medical rehabilitation of patients after aortocoronary bypass grafting at the resort with the use of combined physiotherapy].

The purpose of the work is study of efficiency of medical rehabilitation of patients after aortocoronary bypass grafting on the resort stage with the use of combined electric, electromagnetic, quantum and microvibration therapy. 150 patients were randomized in three groups. First group (75 persons) together with the basic treatment (antiaggregants, beta-blockers, statins) received combined electric, electromagnetic, quantum and microvibration therapy.

[Clinicofunctional characteristics of patients with ischemic heart disease after coronary artery bypass surgery as shown by 5-year follow-up].

Aim: To assess immediate and 5-year follow-up results of coronary artery bypass surgery (CABS) in patients with ischemic heart disease (IHD).

Material And Methods: Psychophysiological state (severity of myocardial lesion, psychological status, blood lipids) was evaluated in 58 IHD males aged 44 to 59 (mean age 53.7 +/- 4.

[Effectiveness of vilarinum, a natural adaptogen, in rehabilitation of patients after coronary bypass surgery].

The purpose of the study was to evaluate the clinical effectiveness of vilarinum, a natural adaptogen, in the complex rehabilitation of patients with CHD after coronary bypass surgery (CBS). The subjects were 130 patients, whose sanatory treatment began 28.3 +/- 3.

[Cardiac glycosides in complex treatment of patients with heart failure and supraventricular arrhythmias].

The authors of the article studied potential of various drug combinations (atenolol + enalapril + indapamide, and celanid + enalapril + indapamide) in complex treatment of patients with heart failure (HF) and supraventricular arrhythmias. The subjects were 106 patients, of whom 74 had coronary heart disease, of whom 51 had old myocardial infarction, and 18 had undergone coronary artery bypass grafting. Dilatation cardiomyopathy was found in 8, aortomitral valvular disease--in 18, and combined mitral valvular disease--in 6 patients.

[The dynamics of clinical and functional condition of patients with different variants of coronary heart disease course during the period of long-term outpatient follow-up].

With the purpose to study clinical and functional parameters of coronary heart disease (CHD) course, the authors carried out a complex examination of 376 patients (308 men and 68 women). The evolution of their psychophysiological condition was evaluated after 1, 3, 5, and 7 years. 3 variants of disease course were distinguished: 1--clinical remission--was observed in 27 (7.

[Assessment of anti-arrhythmic efficacy of a domestic drug allapinin in patients with ischemic heart disease and cardiac arrhythmia].

Antiarrhythmic activity of oral allapinin was studied in 64 patients with ischemic heart disease. 27 of the patients had undergone coronary artery bypass grafting 2 to 12 months before, 19 patients had postinfarction cardiosclerosis, 38--arterial hypertension, 30--circulation insufficiency stage I. Arrhythmia presented as ventricular extrasystole (n = 28), paroxysmal atrial fibrillation (n = 18), paroxysmal atrial tachycardia (n = 11), frequent supraventricular extrasystole (n = 7).

[Improvement of the rehabilitation system of patients after aortocoronary bypass].

Using the significant representative sample the important conclusion was drawn about the necessity of patient early differentiation on the base of psychosomatic status evaluation. The algorithms of treatment measures were developed on the base of which two rehabilitation patterns were created. It is shown that the use of the patterns developed permits to decrease the treatment expenses (the important factor in modern conditions).

[The effect of personality traits on rehabilitation of patients with ischemic heart disease after aortocoronary bypass].

The course of ischemic heart disease (IHD) was studied in patients who had undergone coronary artery bypass operation with consideration of types of emotional and behavioral activity. A total of 83 IHD patients were examined using Jenkin's questionnaire. Clinical and psychophysiological characteristics of patients with different behavioral types are described.

[Clinical and cost-effective aspects of nitrate therapy in patients with ischemic heart disease after aortocoronary bypass surgery].

The purpose of this study was to evaluate the efficiency of Mono Mac 40, nitrosorbide, and sustac forte in the treatment of coronary patients with incomplete revascularization of the myocardium after aortocoronary bypass surgery (functional class III). The patients (n = 112) were divided into 3 groups: 1) 36 patients treated with sustac-forte in a daily dose of 38.4 mg, 2) 37 patients treated with nitrosorbide in a dose of 80 mg, and 3) 39 patients treated with Mono Mac 40 (isosorbide-5-mononitrate) in a dose of 40 mg.

[Use of a program of medical and psychological support in patients with ischemic heart disease, having undergone aortocoronary shunting].

167 patients with aortocoronary bypass were treated in the sanatorium ("Arkhangelskoye") and then for a year were treated outpatiently. Of them, 127 patients have additionally undergone training according to the program of medical and psychological rehabilitation. 40 control patients have not been trained.

[The medical rehabilitation of servicemen following aortocoronary bypass].

The results of aortocoronary shunting (ACSh) were studied in 243 patients after myocardial infarction at different stages of rehabilitation--in rehabilitative hospital and military sanatorium. Result assessment at the final stage of therapy in sanatorium confirmed ACSh efficiency in overwhelming majority of patients. At the same time principal peculiarities were revealed showing the necessity of differential approach to determination of volume and place for conduction of restorative therapy.

[Program of medical and psychological support of patients after cardiosurgery].

Aim: To study effectiveness of the program of medical and psychological support of patients after aortocoronary by pass operations (ACBO).

Materials And Methods: The trial included 108 patients with coronary heart disease (CHD) after ACBO. 72 patients of the test group participated in the program of medical and psychological support.