In experiments with two tissue culture lines it was shown, that cytotoxicity of mercury (1) derivatives (measured by CL50) is lesser two times, than it was for mercury (2) derivates. No significant differences in cytotoxicity were noted by the cell morphology and monolayer mitosis activity coefficient studies. This demonstrates the equal toxicity and dangerous to both derivates.
View Article and Find Full Text PDFWorkers engaged in the production of inorganic manganese salts revealed lesions of the upper respiratory pathways (catarrhal and subatrophic rhinitis, pharyngitis, laryngitis), skin (contact and allergic dermatitis), cardiovascular disorders. They also showed changes of renal function,mineral metabolism,acid stability of erythrocytes. Activation of the B-system of immunity and allergization of the body are also observed.
View Article and Find Full Text PDFIt was established that the major hazardous substances in cobalt acetate, chloride, nitrate and sulphate processing shops were the finished product's dusts (disintegration aerosol) in concentrations from 0.05 to 53 mg/m3 depending on the stage of the technological process. An analysis of morbidity with temporary disability and the rate of the workers' appliance for medical advice showed, among the major groups of industrial workers, particular prevalence of the upper respiratory tract diseases (rhinitis, pharyngitis, laryngitis) and the signs of irritation of the mucous in the eyes.
View Article and Find Full Text PDFThe workers engaged in the processing of the UP-671, UP-671D, UP-677, UP-680 and UP-682 epoxide resins are influenced by both initial and intermediate industrial products, as well as the resins' volatile components in MAC threshold concentrations. The workers engaged in major professions displayed upper respiratory allergic diseases, contact and allergic dermatitis, sensibilization to epichlorhydrine, staphylococci and kidney allergen. Euthyroid goiter was diagnosed in most workers, along with thriiodothyronine decrease in blood serum and a higher rate of chromosomal aberrations in lymphocytes.
View Article and Find Full Text PDFIt was established that industrial shops engaged in zinc compounds' processing were characterized by considerable temperature shifts, relative humidity and air motion changes. In drying and packing shops, concentrations of the final product dusts were established at 0.8-2 mg/m3.
View Article and Find Full Text PDFThe professional noxae for workers engaged in production of cobalt acetate, chloride, nitrate and sulfate is dust of the final product in the form of aerosol disintegration. The main professional pathology is manifested in hypertrophic defensive processes in the upper respiratory tract, in contact dermatitis, cardiac disorders of different severity grades. Clinico-biochemical investigations revealed a clear increase of the content of urea, rest nitrogen, glucose, cholesterol and electrolytes (sodium and potassium) in the blood.
View Article and Find Full Text PDFThe proposed study of the immunologic reactivity state in chemical plant workers revealed humoral and cellular reactivity changes caused by chemical agents and the workers' immunologic background. It was established that cobalt and manganese salts caused initial immune response.
View Article and Find Full Text PDFIt was established that the major hazardous factor in nitrate, sulphate and manganese basic carbonate processing shops was the dust of the final product. Upper respiratory tract (catarrhal, subatrophic rhinitis, pharyngitis, laryngitis), skin (allergic and contact dermatitis) and cardiac disorders were specified as the predominant pathology among manganese compounds processing shop workers. Mineral exchange disorders, lowered glucose content in the blood and violation in the acid persistence of the erythrocytes were revealed through medical examinations.
View Article and Find Full Text PDFMed Radiol (Mosk)
September 1988