[Regulation of blood circulation in the surgical correction of portal hypertension].

56 patients with portal hypertension were examined who underwent decompressive shunt surgery. Cardiorhytmography and integral rheography body were performed in different stages. In the late postoperative period, there were positive changes in the autonomic regulation of functions: reduced tension index and sympathetic influence on heart rhythm, increases the value of other indicators of heart rate variability.

[Single-stage operations for synchronous multiple primary and metastatic cancer of the lung and other organs].

The work presents an experience with the diagnosing of synchronous tumors of double localization in 256 patients. Operations were performed on 146 of them. Single-stage operations were made in 55 cases.

[Diagnosis and correction of pathological changes of the tracheobronchial tree during lung surgery].

In 32% of patients operated on the lungs various changes in the tracheobronchial tree develop as early as during the surgical intervention. They are of determining significance in pathogenesis of postoperative disorders in the external breathing function. Bronchoscopy is the most effective method of diagnosis and of timely correction of these disorders during operation on the lungs.

[General biological characteristics of the etiology of postoperative complications in patients with surgical diseases of the lungs].

The causes of lethal outcomes (n = 60) and postoperative complications which occurred in 26.1% of 610 patients operated on for lung cancer were investigated with due consideration for the regularities of thermodynamics of nonequilibrium processes and theory of disasters. A total systems pathological inflammatory reaction, which augments the injury by many times and develops as a result of inadequate anesthesiological protection, underlies the development of the most unfavorable variant of response to surgery leading to life-threatening complications, such as pneumonia, thromboembolism, or ulcerative hemorrhages.

[Anesthesia in severe combined gunshot and mine blast injuries].

An experience with 350 anesthesias in severely wounded patients is analyzed. Two main tasks had to be solved for successful treatment. The first one is the creation of compensation by the infusion-transfusion therapy.

[Preservation by anesthesia management of the normal functioning of the external respiration system following surgery of the upper abdominal organs].

The impact of different variants of neuroleptanalgesia (NLA) on respiration immediately after gastric resection and cholecystectomy has been studied in two homogeneous groups of patients (30 persons each) after operations on the upper abdominal organs. In patients of group I NLA was performed using fentanyl (initial dose--7.5 micrograms/kg, maintenance dose--100 micrograms) supplemented with epidural blockade and isovolemic hemodilution.

[Pathophysiological substantiation of using fasting-diet therapy in the treatment of certain categories of patients].

It is not advisable to prescribe any types of the diet to patients with acute surgical diseases of the abdominal cavity in the early postoperative period because of membranous digestion disturbances and intestinal motility dysfunction. The fasting of the patients with the normal nutritional status may be based physiologically in such cases till the recovery of digestive function, since it favours significant desensitization, namely a decrease of the number of postoperative complications and creation of functional rest for the intestine.

[Pulmonary complications of severe craniocerebral injuries and their prevention (clinico-morphologic aspects)].

Prevention of pulmonary complications according to the generally accepted principles was conducted in 47 patients with severe craniocerebral trauma (control group). At the same time, 32 patients were subjected to a high long-term peridural block at the Th2-6 level (main group). Pneumonia developed in 59.

[Dependence of the cardiac pumping function on arterial resistance in lung cancer and in the stages of its surgical treatment].

The relationship between the arterial resistance and pumping function of the heart was studied in 203 patients by the method of integral rheography. An inverse relationship between the pumping capacity of the heart and vascular resistance was confirmed at different stages of examination and treatment of the patients. The maximal levels of increase of the minute blood flow volume were established as well as the conditions under which the increase of the cardiac output discontinued despite the decrease of the postexercise.

[Characteristics of the diagnosis and prevention of pulmonary complications of severe cranio-cerebral injuries].

Under study was the clinico-roentgenological dynamic of the lung state in 79 patients with severe cranio-cerebral trauma. High continuous peridural blocade performed from the moment of admission to the hospital was shown to prevent the development of hard reactive alterations in the lungs. This method however fails to control acute severe aspiration pneumonia.

[Individual characteristics of the behavior, learning and adaptation of rats exposed to extreme conditions].

Techniques of open field, instrumental food conditioning and acute hypoxic hypoxia were used in experiments on white rats which had been divided into three groups: low--(I), middle--(II) and high-entropy (III). The III group rats were characterized by high motor activity, various postures and states which seemed to account for fast instrumental conditioning of these rats. Rats of the II and III groups (67% of all the rats) proved most resistant against hypoxia and therefore more adaptable to extreme factors.

[Pathogenetic characteristics of cardiogenic shock in closed chest injury with cardiac contusion].

An analysis of clinico-laboratory examinations of 60 patients with a suspected contusion of the heart in an isolated and associated trauma of the chest and experimental investigations on 46 dogs have shown that the closed trauma of the chest with a contusion of the heart is accompanied by disorders of the contractive function of the myocardium and hemodynamics which contributes to the development of cardiogenic shock.

[Effect of high long-term peridural blockade on the indicators of cellular and humoral immunity in severe cranio-cerebral trauma].

The investigation of indices of the humoral and cell immunity in 48 patients with severe cranio-cerebral injuries and results of high prolonged peridural blockade in 21 patients has shown the efficacy of this curative measure for preventing "shock lung". The blockade has been found however to inhibit indices of immunity and should not be longer than 48 hours.