[The diagnostic significance of the ratio of the indices of the pro- and antioxidant systems of the peripheral blood in preventing complications in patients after operations on the soft tissues of the face and neck].

Surgical interventions on soft tissues of the face and neck induce a nonspecific reaction of the body, activating the nonenzymic antioxidative system for regulation of lipid peroxidation processes. The activity of this system is suppressed in pyoinflammatory complications of postoperative wounds, whereas the level of free-radical processes persists high and impaired regulation of lipid peroxidation results in prolongation of all phases of the wound process and in longer wound healing. At the same time a reduction of ceruloplasmin and transferrin levels in the first 24 hrs after surgery may be used as diagnostic test in postoperative pyoinflammatory complications.

[The assessment of the course of the wound process after surgical interventions on the soft tissues of the face and neck by indices of the free-radical oxidation of the peripheral blood].

Interventions in surgery on soft tissues of the face and neck cause a nonspecific response of the body, which mobilizes functioning of the enzymic antioxidative complex. Pyoinflammatory complications in the postoperative period are associated with impairment of the total antioxidative mechanism of the body. These data may be useful in the early diagnosis of complications and in the development of a pathogenetic strategy for the prevention and treatment of postoperative wounds.