[Local immunity and methods for its assessment upon exposure to ambient air-polluting biologicals].

The investigators studied the impact of biological air contamination by the dusts resulting from protein feedstuff manufacture and grain on local immunity of the mucosae in children and adults living in the areas that were differently distant from industrial objects, the sources of contamination, as well as in workers of the shops contaminated by dust containing various amounts of protein. The studies showed that the workers of a biochemical plant exhibited a considerable change in the majority of immunological parameters (lysozyme activity, heterophile antibody titers, salivary and skin bactericidity, salivary total and R-protein, and immunoglobulins A, M, G, and E). There was a significant decrease in salivary IgA activity.

[The prospects of application of methods of population immune status evaluation when performing mass hygienic studies].

Non-invasive methods of sampling and a range of immunological assays for mass ecologo-hygienic studies of population were developed and introduced into practice in Sysin Scientific Research Institute of Human Ecology and Environmental Hygiene of Russian Academy of Medical Sciences. The studied materials were saliva, urine, breast milk, the condition of lymph nodes, and anamnesis. The complex of non-invasive methods was shown to be less complicated and, at the same time, informative and cheap, which allows recommending it for sociohygienic monitoring when performing mass hygienic studies.

[Substantiation of MAC of crotonaldehyde in environmental air].

The reflex and resorptive effects of crotonaldehyde was studied. The maximum acceptable concentration (MAC) of crotonaldehyde was established to be 0.025 mg/m3, the mean daily MAC recommended to be 0.