Publications by authors named "Iu N Liashchenko"

The aim of the study is the improvement of nutritional support by immuno nutrition of patients, who are in critical conditions. The data on the impact of immuno active mixes (on the example of the mixture of Impact) on the immune and inflammatory response. In this, the number of postoperative infectious complications have been reliably decreased, the duration of the stay in the Department of R&IT and the hospital has been dicresed in whole, the cost of treatment in comparison with the use of standard schemes of patients with surgical and oncological profile has been significantly reduced.

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A comparative analysis of current practical recommendations on parenteral (PN) and enteral (EN) Nutrition in critical conditions, developed based on research evidence ASPEN/SCCM (USA), ESPEN (Europe) and SSGP (Canada) along with the similarity found a number of differences in major issues (raised levels of research necessary for the class of recommendations, t he need for and terms of use of PN, glycemic control, achieving the target level of EN), and private (indirect calorimetry, of the EN, the use of individual substrates in PN) as well. The differences make it difficult to select recommendations for use in clinical practice. Over 50% of practical advices are lower grade (based on expert opinion).

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The article provides a history of research in the field of enteral nutrition, history of the mixtures for tube alimentation. Also presented classification of the present mixtures for enteral introduction, as well as a characteristic of each of them.

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The article deals with the analysis of works of S.S. Yudin's students and followers devoted to scientific practical and scientific-organizational research into optimization of infusion-transfusion therapy in emergency service hospitals in emergency states: multiple and combined trauma, the crush syndrome, burns, exogenous poisoning, and pyoseptic complications in surgical and traumatological practice.

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Among 115 patients with gastroduodenal hemorrhage 60 received nonoperative treatment, 30 of them underwent enteral correction with a monomer electrolyte solution. Emergency operation was carried out on 55 patients, 35 of them were subjected to enteral correction in the postoperative period. Enteral administration of the monomer electrolyte solution in the early posthemorrhagic and postoperative periods promoted filling up of the blood circulation volume and its components and stabilization of the values of central hemodynamics.

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The results are presented of the mathematical program "Artificial Feeding" that has been developed for the evaluation of the nutrition status and effectiveness of parenteral and enteral tube nutrition. On the basis of the combination of anthropometric, biochemical and immunological parameters the program makes possible a dynamic follow-up of the patient's nutrition status, calculation of nitrogen, electrolyte and water balances, and determination of the requirements in energy and protein preparations for artificial feeding.

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In polyfistulae dogs, deceleration of protein hydrolysis, of nitrogen, potassium and water absorption in the ileum distal portion as compared with the proximal one seems to be associated with own abilities of the distal areas for nutrients hydrolysis and transport rather than with their evacuatory activity. Different ways of creating polycomponent mixtures for administration into the ileum distal areas, are discussed.

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Chronic experiments on semi-fistula dogs with temporal-isolated parts of the small bowel were made to study the rate of nitrogen, glucose, lipid, sodium, potassium, calcium and water absorption from protein enteral nutrition and nutritive mixtures prepared on its basis. It was established that a nutritive mixture based on 10% protein enteral nutrition with additives in the form of fatty emulsion and sodium chloride was quite suitable for transintestinal administration. The increase of the concentration of protein enteral nutrition administered transintestinally or its preliminary hydrolysis by gastric juice resulted in the enhancement of evacuatory function of the small bowel.

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In poly--fistula dogs, a significant suppression of the fermentative hydrolysis and of the absorption ability was revealed in excluded from the digestion intestinal loops. The experiments showed that suppression of the cave enzyme sorption in the area of wall digestion was the factor slowing down the flow of feeding substances from the enteral milieau.

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