[Surgical treatment of aortic arch malformations in infants under cardiopulmonary bypass].

Aim: To evaluate long-term results and the causes of complications in congenital obstructive pathology of the aortic arch.

Material And Methods: Retrospective study enrolled 62 patients aged 55 ± 14 days who underwent aortic arch surgery under cardiopulmonary bypass. It was compared two methods of aortic archplasty: use of xenopericardial material in group 1 and Rajasinghe's autoplastic method in group 2.

[Results of surgical treatment of the anomalous origin of the left coronary artery from the pulmonary trunk].

The experience of the federal medical center of the surgical treatment of small patients with the anomalous origin of the left coronary artery from the pulmonary trunk was analyzed. The early surgical treatment, directed at the reconstruction of the two sources of myocardial blood supply together with the standard use of "calcium sensitizer" ("Levosimendan") decrease the lethality to 6.6% without the use of extracorporeal membrane oxygenation.

[A response to the correction of congenital heart diseases in infants of the first year of life under extracorporeal circulation].

Examination of 36 infants of the first year of life, who had been operated on under extracorporeal circulation, revealed the activation of the monocytic cellular pool. This reaction was accompanied by an increase in the content of activated HLA-DR-positive cells. Limitation of the monocytic test via apoptotic mechanisms was inadequate.

[The role of specific endothelial granules in changes of myocardium microvessel reperfusion at open-heart operations under hypothermia].

For patients with congenital heart defects, a comparative analysis was carried out of specific endothelial granules and morphological properties of perfusion capacity of microvessels at various stages of reperfusion after prolonged circulatory arrest. At all stages of reperfusion, the quantity of specific granules in microvessel endothelium dramatically dropped, as compared with the control group. At the early stages of reperfusion, the level of granule exocytosis does not lead to any statistically significant changes in perfusion characteristics in the right atrium microvessels, as compared with the control group.

[The comparative morphology of the specific endothelial granules in the microvessels of the hypertrophied myocardium in patients with congenital heart defects and in experimental animals].

Specific endothelial granules of myocardial microvessels were studied in both patients, suffering from different congenital heart pathology, and dogs, before and during hyperthermia. In the intact myocardium of dogs we found two morphological varieties of granules, dark and light ones. The ultrastructural polymorphism of these granules was due presumably to hyperthermia.