The application of technique for obtaining the tibial fragment (split) with a preserved vascular network of the nutrient artery and its branches, that participate in the blood supply of this bone area, permits to detect significant osteogenetic potential of both endosteum and undifferentiated bone marrow cells. Under these conditions it was possible to increase the bone thickness 2 to 3 times in short time. The regeneration process in this case is characterized by a rapid course and formation of large massive of cancellous bone.
View Article and Find Full Text PDFHigh molecular fraction of HCl-extract from mature homologous bone was parenterally administered, during the predistraction period, into 16 rabbits, crus of which was elongated by Ilizarov procedure. The treatment affected positively the adaptation process, hemopoiesis and the ossification of distraction regenerate. Administration of the high molecular protein fraction into mice with depressed hemopoiesis demonstrated that physiological effect of the fraction consisted in stimulating effect on proliferation of both bone tissue and red blood cells.
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