[Results of using biocoating by means of the amniotic sac. Communication 2. Biocoating for the treatment of keratitis].

The amniotic sac has recently come into wide use to treat patients with various corneal lesions. Its suture fixation to the conjunctiva has proven to be inadequate, which limits its therapeutic effect. It is not quite expedient to use a donor corneoscleral flap for amniotic sac fixation in the existing shortage of a plastic material for keratoplasty.

[Results of using biocoating by means of the amniotic sac. Communication 1. Keratoplasty with graft biocoating].

To protect a corneal graft at keratoplasty from tear moisture hyperhydration of the de-epithelized surface and from the negative exposure to contact with the eyelid mucosa in order to enhance surgical efficiency, the authors have developed a few biocoating technologies that involve amnionic sac placement on the graft, with its fixation on the eye of a recipient, by applying a full-thickness and layered corneal disc autologous flap or a ring-shaped allogenic corneoscleral one. Fifty-two patients (55 eyes) with primary (n=5) and secondary (n=33) corneal dystrophy and leukomas (n=14) were operated on. Penetrating keratoplasty and layer-by-layer grafting were performed in 38 (40 eyes) and 14 (15 eyes) patients, respectively.