[Complex automatic data processing in multi-profile hospitals].

The computerization of data processing in multi-disciplinary hospitals is the key factor in raising the quality of medical care provided to the population, intensifying the work of the personnel, improving the curative and diagnostic process and the use of resources. Even a small experience in complex computerization at the Botkin Hospital indicates that due to the use of the automated system the quality of data processing in being improved, a high level of patients' examination is being provided, a speedy training of young specialists is being achieved, conditions are being created for continuing education of physicians through the analysis of their own activity. At big hospitals a complex solution of administrative and curative diagnostic tasks on the basis of general hospital network of display connection and general hospital data bank is the most prospective form of computerization.

[Experience in computer-assisted construction of a decision rule for assessing the severity of the condition of patients with severe mechanical injuries during the posttraumatic period].

A retrospective analysis was made of clinical and laboratory findings from 96 patients admitted to a general resuscitation unit for severe mechanical injury and shock. The degree of experienced shock, score rate of shock production in an injury, parameters of central hemodynamics, biochemistry and coagulogram of mixed venous blood, acid-base balance of arterialized capillary blood were analyzed in all the affected patients. The data were processed by a computer by widely using the multifactor regression analysis and special conversion of homeostatic values.

[Characteristics of the functioning of the oxygen supply system on the 1st day following trauma in patients with various courses of the post-traumatic period].

A correlation between a number of oxygen balance parameters and the application of regression analysis methods has been studied in 67 patients within the first 24 h after trauma. The regression equations demonstrate that O2 transport (TO2) reserve sufficient to meet high metabolic requirements in the first 24 h after trauma promoted prompt normalization of the vital body functions and a more favourable course of the posttraumatic period. The formula has been derived and a nomogram has been plotted for the calculation of TO2 reserve in the first 24 h after trauma.

[Effect of irradiation on the size of isolated liver mitochondria].

The role of external effects in the time course of changes in hepatocyte mitochondria size was studied. Suspensions of mitochondria isolated from the liver of inbred mice were investigated at various periods after gamma irradiation. Statistical analysis of changes in the size of isolated mitochondria has shown that irradiation leads to an increase in mitochondria size, reflected in the distribution pattern.