[Possibilities of culturing Cryptosporidia in the cell-free medium].

An attempt was made to culture the Cryptosporidia, which had been isolated from the excreta of 24 HIV-infected patients and prepassaged on SCID mice, in an artificial host cell-free medium. The authors examined their impact of rabbit hepatic and renal tissue extracts, hemolyzed rabbit blood, bovine bile, ATP, calves' embryonic serum, bovine serum albumin, glucose, phytohemagglutinine, and concanavalin A, cultivation temperature, and medium pH on growth culture. A total of 72 cultures were tested.

[Evaluation of the efficiency of multiple coproprological study for the diagnosis of giardiasis].

Reformation of public health system financing in Russia requires the use and distribution of the most effective and least expensive diagnostic and medical methods. Giardiasis is the most common human anthroponosis. The diagnosis and treatment of this disease call for considerable funds of the budget, medical insurance companies, and the patient himself/herself.

[The use of clinical, immunogenetic and immunological indices for predicting the development of the recurrent form of erysipelas of the lower limbs].

A consecutive alternative analysis has been carried out of clinical, immunogenetic and immunological indices in patients with primary erysipelas of the lower extremities with and no recurrences during the last 3-5 years. The authors compiled a special scale allowing precise and early prediction of unfavourable, recurrent course of primary erysipelas of the lower extremities.

[Effect of indirect endolymphatic antibiotic therapy on clinical and immunological indicators in patients with erysipelas of the lower extremities].

Two groups of patients with erysipelas of the lower extremities underwent indirect endolymphatic therapy with bicillin-3 (58 patients) and routine penicillin therapy (79 patients). Comparative clinicoimmunological examinations in the two groups revealed that lymphotropic administration of the antibiotic had a more favourable effect on the disease process, as evidenced by more rapid reverse time courses of erysipelas clinical signs, less frequent incidence of early relapses and normalization of the majority of immunological parameters by the end of the treatment. For estimation of the anti-recurrence efficacy of the antibiotic therapy in the patients with erysipelas, it was recommended to use a specific scale based on the principles of the Wald successive alternative analysis.

[Changes in the kallikrein-kinin system of patients with erythematous and hemorrhagic forms of erysipelas].

The state of the kallikrein-kinin system of the blood (KKS): kallikrein (KK), prekallikrein (PK), general arginine-esterase activity (GAEA), alpha 1 inhibitor of protease (IP) and alpha 2-macroglobulin (MG). The initial period of the disease was characterized by an increase of the level of KK, GAEA, IP and MG and a reduction of PK. It was established that the maximal activation of KKS develops in patients with the erythematous form of erysipelas during the first days of the disease, with the hemorrhagic form--on the 2 week.

[The pathogenetic and prognostic significance of the level of class-E immunoglobulins in erysipelas].

The authors determined the content of total immunoglobulins of the E class in the blood plasma: native (IgE) and exhausted by a streptococcal allergen in the dynamics of the disease in 145 patients with erysipelas. The level of antistreptococcal reagins was evaluated. It was established that at the onset of erysipelas the concentration of IgE and a-IgE showed a short-term increase in 52 +/- 4% and 87 +/- 3% of patients correspondingly.

[The use of the kallikrein-kininogen system indices in the prognosis of the development of hemorrhagic erysipelas].

A number of the kallikrein-kinin system parameters (kallikrein, prekallikrein, total arginine esterase activity, alpha 1 protease inhibitor, and alpha 2 macroglobulin) were measured in 59 patients with erythematous erysipelas and in 51 ones with hemorrhagic erysipelas over the course of the disease. Marked activation of the blood kallikrein-kinin system was seen in all the patients during the initial period of the disease, manifesting by elevated levels of kallikrein, total arginine esterase activity, alpha 1 protease inhibitor, alpha 2 macroglobulin, and a lowered prekallikrein concentration. In erythematous erysipelas the peak of activation was recorded in the first days of the disease, whereas in hemorrhagic condition it was observed during the second week of erysipelatous inflammation.

[Characteristics of the course of diphtheria in alcohol abuse].

A comparative study of the diphtheria course was conducted in 46 patients who denied taking alcohol or who used it not more than once a month and in 21 patients who used alcohol continuously. A more severe course, complicated forms of diphtheria and fatal outcomes were more frequently encountered in the latter group of patients.

[Determination of haptoglobin phenotypes using electrophoresis in viral hepatitis B, HBsAg carriers and normal subjects].

Haptoglobin (Hp) phenotype distribution has been examined in 193 patients with an acute icteric form of hepatitis B (HBsAg+), in 36 chronic HBsAg carriers, and in 317 normal controls. The incidence rates of three Hp types have been virtually the same in the acute patients and in the controls. In chronic HBsAg carriers the Hp 1-1 type has been detected 3 times more frequently than in acute hepatitis B patients and 4 times more frequently than in normal subjects.

[A rare case of the meningoencephalitis form of the Loeffler syndrome].

The article describes a case of benign meningoencephalitis attended by marked eosinophilia. The disease was evaluated as a meningoencephalitic form of Loeffler's syndrome. Drug-induced allergy is considered as a possible cause of the disease.