Publications by authors named "Iu Kh Sarkisian"

A study was made of the condition of 44 acromegalic patients at various time after gamma-beam therapy. It has shown that therapeutic efficacy depends on initial sizes of adenomas and the level of growth hormone as well as on the time of observation. At late terms after therapy normalization of the level of growth hormone was observed in 41% of patients, clinical improvement in 44%, the absence of and effect in 15%.

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A system of automated control Aspect-2 was developed for automation of gamma-beam therapy on units of the Rokus series. The system consists of the following hardware and software complexes: a complex of preirradiation preparation "Centrator-imitator"; a complex Accord for anatomotopographic data coding; a software complex and a gamma-therapeutic complex Rokus-AM. The Centrator-imitator and Rokus-AM complexes are fitted out with built-in microcomputers with specially developed systemic software.

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The paper is concerned with the substantiation of multifractionated gamma-beam therapy and the results of the use of this regimen in radiotherapy of rectal cancer. The authors have proposed the following scheme of irradiation: a single focal dose of 2 Gy is delivered not once a day as in routine fractionation but twice a day with a 4-hour interval. A radiotherapeutic course has been divided into 3 stages of 5 days each with 5-day intervals in-between.

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The authors present a technique of concomitant radiotherapy of rectal cancer using 60Co movable sources of the Agat-B unit for contact irradiation. The paper is illustrated with the schemes of radiation sources in relation to tumors and pictures of dose fields formed by various radiation sources and positions as well as their time intervals in each position during a therapeutic session. The results of treatment of patients in the main group (47 persons) and in the control group when the patients received gamma-beam therapy only (45 persons) are also given in the paper.

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The authors present the results of the use of dibunol in the form of liniment (1-10%) for the treatment of radiation cystitis and rectitis resulting from radiation therapy of small pelvic tumors, epidermitis and epithelitis that develop in the course of treatment of skin and lower lip tumors. A high efficacy of the drug in the therapy of radiation injury has been shown in 212 patients.

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Nine lung cancer patients were subjected preoperatively to radiotherapy under hypoxia with inhaling of GHM-10 (gas hypoxic mixture). The patients were followed up during 7--12 months. The results obtained evidence the rationality of further studies in this direction, that is of special importance due to introducing of reconstructive--plastic operations on the trachea and bronchi into oncological practice.

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