[Changes in lipid fractions of blood during the treatment of hypertension with prazosin and trasicor].

The paper deals with the study into the benefits of prazosin and trasicor used in arterial hypertension. Their effects on the blood lipid composition were evaluated. With prazosin, the steady antihypertensive effect was reached in 81.

[Determination of the specific points in the atrial excitation sequence on the P loop of the VCG by using the parameters of a differentially amplified ECG].

Ninety-eight normal subjects and 31 patients with right, left or bilateral atrial enlargement were examined, with differentially-amplified atrial electrocardiogram (DAECG) and intensified atrial vectorcardiogram recorded simultaneously. Atrial complex DAECG permitted an accurate determination of the following sequence of specific atrial activation points on the P loop of vectorcardiogram: activation along the right atrium only (before the left atrium is included), the origin of left atrial activation, the termination of right atrial activation and the maximum vector of the left atrium. Determining the maximum vector according to the most distant point on the P loop is not practicable, because of its ambiguous representation of atrial activation processes.

[Changes in the indices of the atrial complex on a differentially amplified ECG in atrial infarct].

The atrial complex of differentially amplified ECG was examined in 19 patients with atrial infarction. The diagnosis of atrial infarction was based on the electrocardiographic features, and in 7 cases it was confirmed by postmortem examination. The electrocardiographic pattern was characterized by P-Q segment shift.

[Use of differential methods for analyzing electrocardiograms in the diagnosis of supraventricular arrhythmia].

Differential-gain ECG (DG-ECG) recordings were made to investigate the mechanism of tachyarrhythmias. The study comprised experimental and clinical series. Experimental findings demonstrated two types (local and circulatory) of vulnerability manifested during induced tachyarrhythmia.

[Relation between intra-atrial conduction and disorders of sinoatrial, atrioventricular and intraventricular conduction (according to selectively intensified ECG findings)].

The differentially intensified ECG was recorded from the chest surface to determine the intraatrial conductivity in patients with chronic coronary heart disease. The parameters of the differentially intensified ECG were compared with the indices of intraatrial conductivity on the intracavitary electrogram. Disorders of intraatrial conductivity were also compared with impairments of conductivity in other sites of the conductivity system of the heart.

[Significance of a differentially amplified ECG in the diagnosis of paroxysmal tachycardias].

For differentiation of tachycardias the authors offer a method of recording the curves of differentially increased spike potentials (DISP) of atriae from the surface of the chest wall, based on the recording of the electrical activity of the atriae in the shape of a high amplitude atrial spike complex. The DISP curves have been recorded in 36 patients with tachycardias, in whom by usual ECG it was difficult to determine the tachycardia type, in some cases it was impossible, for instance in confluence of the P wave with the QRS complex or the T wave. The typical and constant form of the atrial spike complex on the DISP curve in the sinus rhythm permits determining the sequence of the stimulations of atriae and the type of disorders of the cardiac rhythm.

[New diagnostic method in arrhythmias and heart conduction disorders].

The authors developed a method for recording spike potentials of the heart conduction system from the body surface on a curve of differentially intensified spike potential (DISP). They examined 187 patients and 60 healthy persons. The spike potentials of the sinoatrial node, atria and the bundle of His recorded on the DISP curves coincide exactly in time with spike potentials on intracardiac ECG recorded by microcatheterization of the heart through the subclavian vein, which makes it possible to distinguish on the DISP curve reference points for determining conductivity on definite areas of the heart conduction system.

[Direct recording of electrical activity of human sinoatrial node].

The authors developed a method for recording the electrical activity directly from the human sinus node through the right subclavian vein. Electrical activity of the sinoatrial node (SA) was studied in 179 patients with CHD (angina pectoris, myocardial infarction). The sick-sinus syndrome (SSS) was revealed in 86 patients.

[Method of recording the diagnostic value of the electrocardiograph of the bundle of His].

A method of cardiac microcatheterization introduced by the authors and effected by puncturing the left subclavian vein with a microcatheter of their original design permits recording the bundle of His electrogramme in a functional diagnosis study or in an intensive care ward. The bundle of His electrogramme was recorded in 107 patients, 72 of them having ischaemic heart disease, and 35 -- other cardiac lesions. The obtained data support the high diagnostic value of the bundle of His electrogramme, especially in determining the level of the atrioventricular block, of the reentry phenomenon, in differentiating abberant QRS complexes from ventricular extrasystoles, in diagnosing ectopic rhythms from different parts of the conductive system of the heart, and other complicated arrhythmias.