The paper presents evaluation of HLA-system functional activity in patients with pulmonary tuberculosis and bronchial asthma by expression of class I and II antigens and beta2-microglobulin level in peripheral blood cell elements. Tuberculous patients had reduced production of beta2-microglobulin in the cell elements. Long-term chemotherapy aggravated the above abnormality.
View Article and Find Full Text PDFIn bronchial asthma alone and combined with active pulmonary tuberculosis there are marked shifts in immune system (diminished mature T-cell and suppressor subpopulation of T-lymphocytes) resulting in disordered immunoregulatory subpopulation relationships. Also, B-system immunity responded with hyperfunctional activity (increased count of B-lymphocytes and polyclonal gammaglobulinemia). As conventional methods fail to normalize the shifts, an adjuvant laser immunocorrection was tried.
View Article and Find Full Text PDF