[System preserving radiation safety for Moscow population].

Radiation safety system functioning on Moscow territory enables to control potential dangerous sources, opportunely reveal and liquidate accidents and pollutions, forecast degree of radiation jeopardy according to its components.

[Small doses of ionizing radiation as radiation modifying factor].

To investigate the biological effects of small dose ionizing radiation has been acquiring greater importance. The awareness of how and in what direction it show its modifying effects in small doses is an essential scientific basis for developing standards, living conditions under specific environmental conditions. Cultured Hela cells and DEF 4/21 fibroblasts were used to evaluate the biological effects of small-dose ionizing radiation, by examining the conditions under which it showed its modifying effect in small doses (0.

[The adaptational intracellular mechanisms regulating energy homeostasis during intermittent normobaric hypoxia].

Rats trained to intermittent normobaric hypoxia (INH) developed an increase of the glycogen contents in the heart and liver parenchymatous cells. Fatty acids seem to be the main source for synthesis of the intracellular glycogen. The intracellular transformation of the lipid energy substrate into the carbohydrates maintains the energy homeostasis in hepatocytes and cardiomyocytes during hypoxic intervals of the INH thus creating the necessary conditions.

[Status of the blood system and nonspecific anti-infection defense during external irradiation of rats with a low-energy infrared laser].

The epigastrium was irradiated by low-energy infrared Skalyar laser in intact noninbred rats. The energy exposure at 5 and 20 MW was found to be accompanied by the development of leukocytosis at the expense of all types of leukocytes, the extensiveness of early phases of polynuclear phagocytic activity, increases in neutrophilic redox processes and complement titers during 7 days of the experiment. The count of red blood cells, the levels of hemoglobin, and lysozyme enzymatic activity were decreased, hematocrit remained in the normal ranges.

[A comparison of different methods for quantum hemotherapy in treating complicated forms of acute cholecystitis in middle-aged and elderly patients].

Quantum hemotherapy (QH) was used in complex treatment of elderly and senile patients operated upon for complicated forms of acute cholecystitis. Under examination there were 75 patients. Transfusion of UV irradiated donor plasma was found to be most effective of the QH methods used by us in the complex treatment of acute cholecystitis in elderly and senile patients.

[Homeostatic responses of the body during infusion of UV-irradiated autologous plasma].

Complex examination of changes in some structural and metabolic values in intact dogs after a single infusion of autoplasma irradiated with ultraviolet rays suggests that mobilization of the system of antioxidant protection, inducing a specific reorganisation of the metabolic system, is the trigger mechanism of the organism's adaptation reaction.

[Metabolic shifts and gas exchange during the working of artificial heart ventricles].

Complete cardiac bypass has been performed in the experiments on 21 random-bred dogs under thiopental-ketamine anesthesia using artificial heart ventricles (AHV), "Kedr" type. In 9 dogs 15 hours after AHV insertion their output was increased by half, as compared to baseline cardiac output values; in the rest of animals AHV worked in the regimen of normal perfusion. The study of acid-base balance parameters has revealed that AHV functioning in the regimen of normal perfusion for 2.

[Role of adrenergic regulation in the genesis of myocardial ischemia].

The role of altered adrenergic regulation in the development of myocardial pathology was studied in dog experiments. Activation of the sympathetico-adrenal system was induced by electrostimulation of the sympathetic tonic cardiac nerve in the first experimental series and by intravenous infusion of exogenous noradrenaline (NA) in a dose of 1 microgram/kg/min in the second series. A positive inotropic response of the heart occurred in both series.

[A method of reinfusing ultraviolet-irradiated autoblood in combined modality intensive therapy of pyo-inflammatory diseases in premature infants].

The method of UV-irradiated autoblood reinfusion was used in intensive care of 25 premature babies with pyoinflammatory diseases. On the second day after reinfusion 17 babies showed an improvement of infectious intoxication, decreased level of antigenemia, liquor purification, leukocyte blood count normalization and decreased levels of total bilirubin, residual nitrogen and urea. Within 5 days after the reinfusion the activation of antioxidant blood system and reparative processes was observed.

[Acid-base equilibrium of the blood during treatment using plasma UV-irradiation of chronic diseases of the liver and bile ducts with cholestasis].

Donor plasma irradiated by ultraviolet rays was administered intravenously to patients with choledocholithiasis, chronic hepatitis and liver cirrhosis. Parameters of the acid-base balance of arterialized capillary blood shifted to alkalosis, were normalized, and tension of carbon dioxide and oxygen in the blood increased to physiological values. Dynamic changes of the biochemical parameters demonstrated alleviation of manifestations of the cholestasis syndrome.

[Therapeutic effect of the transfusion of UV-irradiated donor plasma in mechanical jaundice].

The method of intravenous administration of UV-irradiated donor plasma to patients with jaundice of different genesis has been tested in the experiments on rats and used clinically in 20 patients. Biochemical and morphological studies have shown that such treatment causes stable improvement in the liver functional state.

[Changes in the blood system after its extracorporeal irradiation].

One-stage extracorporeal beta-radiation of dog blood in a dose of 6-12 Gy is not followed by the development of radiation after-effects. Favourable changes in the peripheral blood content are marked. Erythrocyte carbohydrates undergo adaptation reconstruction with an increase in the percentage of nucleic acids.

[Intracellular transformation of fatty acids into glycogen in alloxan diabetic rats, based on electron autoradiographic data].

Alloxan diabetic rats were treated with intravenous injections of 3H-oleic or 3H-arachidonic acids. Radioautographs were found in glycogen accumulations in hepatocytes and cardiomyocytes as well as in pure glycogen fractions. The conclusion was made about transformation of fatty acids to glycogen.

[Humoral nonspecific immunity in patients with post-burn cicatrical strictures of the esophagus].

The authors have studied the significance of factors of the humoral non-specific defense (HND) in 37 patients with cicatricial constrictions of the oesophagus and stomach. The data obtained were used for choosing the optimum terms for gastrostoma and oesophagoplasty. In 14 patients treatment with lysozyme was performed due to decreased indices of HND.

[New possibilities of the thermodilution method in studying coronary circulation and intracardiac hemodynamics].

The new possibilities of determining the coronary blood flow and intracardiac hemodynamics by the thermodilution method were studied in experiments on 40 mongrel dogs. A method for measuring the true coronary blood flow without catheterization of the coronary arteries and coronary sinus as well as a modified Holt's method for determining the end diastolic volume of the heart ventricles are suggested. The method is simple and therefore creates favourable prospects for its wide use both in experiments and in clinical studies.