[Pharmacologic and cold therapy in severe chronic ischemia of the lower extremities].

It was demonstrated experimentally and in the clinic that pharmacocoid therapy applied before, during, and after operation produces a protective anti-ischemic and spasmolytic effect, prevents of reduces the intensity of reperfusion disorders, and allows the viability of the limb involved in severe chronic ischemia to be appraised.

[Local hypothermia in the treatment of acute arterial occlusion of the extremities].

An experimental and clinical investigation of the possibility to use local hypothermia of the extremity in the complex treatment of its acute ischemia was performed. It was established that the local hypothermia could considerably improve tissue viability in the process of the extremity ischemia at the expense of spasmolytic, hypocoagulative, anesthetic effects and inhibition of metabolism. A conclusion is made that the local hypothermia should be used in the clinic for the improvement of results of treatment of patients with acute arterial obstruction of the lower extremities complicated by severe ischemia.