[Regulation of erythropoiesis in patients with iron deficiency anemia].

Erythropoietin level in the blood plasma, iron metabolism, and some erythron parameters characterizing anemia expression, erythropoiesis effectiveness and processes of hemoglobin synthesis were studied in patients with iron-deficiency anemia (IDA). The results of the investigation helped the authors to establish that hormone production in IDA patients is under the control of a feedback mechanism that is functioning at a lower level as compared to other non-renal anemias. It has been suggested that optimum possible erythron functioning in IDA patients is achieved under these conditions.

[Study of iron metabolism in chronic diffuse diseases of the liver].

Iron metabolism was studied in patients with chronic diffuse diseases of the liver. A sharp increase of ferritin content at the expense of its release from affected hepatocytes, and formation of antibodies to ferritin of the splenic type have been recorded in patients with cirrhosis of the liver. The observed growth of ferritin content in red blood cells can be explained by functional deficiency of red blood cells and by the presence of hemolytic process (twofold decrease of haptoglobin level).

[The therapeutic efficacy of transfusions of erythrocyte mass in anemia in patients with internal diseases].

The results of the overtime combined clinico-laboratory investigations have evidenced a high medical effectiveness of red blood cell pack transfusions in the treatment of anemia in patients with varying diseases of internal organs.

[Treatment and prevention of iron deficiency anemia].

The paper covers present-day methods of diagnosis, treatment, primary and secondary prophylaxis of iron deficiency anemia. Serum ferritin determination useful for evaluating total iron deposits in the body is thought to allow early diagnosis. Oral administration of iron preparations is recommended as more advantageous.

[Blood components, preparations and blood substitutes in the emergency therapy of patients with liver cirrhosis].

Therapeutic action of blood components, preparations and substitutes was studied in liver cirrhosis patients with deep anemia, marked hemorrhagic complications, endogenous toxicosis, protein insufficiency and rheological disorders. A high efficacy of different media was shown in urgent therapy of liver cirrhosis patients. A choice of drugs was determined by the patients' initial status and specificities of purpose-oriented action of modern transfusion and infusion media.

[Value of the alimentary factor in the prevention of iron deficiency conditions in young children].

On the basis of the clinicophysiological and biochemical-hematologic investigations it was established that the feeding of infants with the adapted mixture "Malysh" did not prevent the development of latent iron deficiency in them. This was the reason for the enrichment of the mixture with hemopoietic substances. Five formulas of the mixture with varying compositions of hemopoietic factors enabled the authors to establish the optimum variant of the ratio of these ingredients in the adapted milk mixture.