[Endovascular radiofrequency denervation of renal arteries as an innovation method of treatment of refractory arterial hypertension. First experience in Russia].

Excessive activation of the sympathetic nervous system forms the basis of pathogenesis of essential arterial hypertension (AH). The present work was aimed at evaluating efficacy and safety of endovascular radiofrequency denervation of renal arteries in patients with AH refractory AH based on the initial first experience in with using this methodology in the Russian Federation. The interventions were carried out on December 14-15th, 2011 in the first five patients presenting with AH refractory to antihypertensive therapy consisting of three and more drugs in therapeutic doses, one of which was a diuretic.

[Value of the spectral analysis of radiofrequency intravascular ultrasound data in the evaluation of nonsignificant coronary lesions in chronic CHD patients].

Plaque complication depends on its composition and phenotype rather than on the degree of stenosis. Plaque rupture predominantly occurs in areas with large lipid core rich in cholesterol and thin fibrous cap. Features of unstable atheromas are mostly described in patients with acute coronary syndromes (ACS).

[Comparison of non-invasive electron-beam and multislice CT angiography efficacy for detection of coronary artery stenosis].

Aim: To compare diagnostic value of electron-beam CT (EBT) and multislice CT (MSCT) angiography in detection of coronary artery stenosis in patients with coronary artery disease (CAD).

Material And Methods: 140 CAD patients who had undergone EBT (n = 97) or 4-slice CT (n = 43) coronary angiography and conventional coronary angiography as a gold standard were included in the study.

Results: Sensitivity and specificity of EBT angiography in coronary stenosis detection (proximal and mid segments) were 86 and 97%, respectively.

[Clinical and economical effectiveness of outpatient diagnostic coronary angiography].

Introduction into clinical practice of transradial coronary angiography (CA) made it possible to conduct the procedure in outpatients and thus increase number of CA and diminish its cost. Aim of the study was to assess possibility, safety and economical efficacy of outpatient CA. Between April 2004 and August 2007 CA was carried out in 133 outpatients without overt heart failure, unstable angina, complex disturbances of cardiac rhythm or conduction.

[First experience with the use of a clip device for closure of arterial approach after endovascular treatment of coronary arteries].

Aim of the present study was assessment of the StarClose Vascular Closure System - novel device for mechanical closure of femoral artery puncture site. We included in this study 29 patients in whom after procedure of endovascular treatment puncture site was closed with the given device. Control group comprised 34 patients in whom hemostasis was conducted by way of manual compression of puncture site according to standard technique.

[Diagnostic value of CT angiography in coronary arteries stenosis detection].

Background: Noninvasive imaging of coronary arteries is very important. CT angiography (multislice computed tomography and electron beam computed tomography -- MSCT and EBT) is most reliable method for noninvasive coronary visualization.

Purpose: The aim of our study was to evaluate the diagnostic value of CT angiography in coronary arteries stenoses detection in patients with coronary arteries disease (CAD).

[An experience of the use of stents with drug coating in patients with long and diffuse coronary artery lesions].

Treatment of long and diffuse lesions of coronary arteries remains one of most complicated sections of endovascular treatment. From 2003 to 2005 treatment with the use of stents with drug coating was conducted in 198 patients with long and diffuse coronary artery lesions. This made up 26% of total number of patients subjected to percutaneous coronary intervention during this time.

[Immediate results of endovascular treatment of coronary arteries in patients with ischemic heart disease].

Aim: To assess immediate results of percutaneous coronary interventions (PCI) and finding the predictors of the successful outcomes in various subgroups of patients with coronary artery disease (CAD).

Material: Patients (n=1066, (average age 55.7+/-9.

[Use of "Cypher" sirolimus-eluting stents in coronary heart disease patients with different types of coronary arterial lesions].

The purpose of our study was to assess the immediate and late results of treatment with Cypher drug-eluting stents (Cordis, Johnson & Johnson, USA) in patients with coronary heart disease (CHD). This was a prospective study that included 738 patients who had been implanted Cypher stents in May 2002 to March 2006. The patients' mean age was 56 +/- 9 years; there were 87% of males.

[First results of stenting of bifurcation stenoses of the coronary arteries].

Aim: To study effectiveness of various types of coronary stenting in bifurcation stenoses.

Material And Methods: Fifty six patients with bifurcation stenoses were divided into 2 groups: stenting of the basic and side branch of the coronary artery (CA) was made in group 1 patients (n = 27), stenting of the basic branch and balloon angioplasty of the side branch were made in group 2 (n = 29). Primary clinical and angiographic response reached 96 and 90% in groups 1 and 2, respectively.

[Early results of endovascular treatment of chronic coronary occlusion in patients with ischemic heart disease].

The early results of endovascular treatment of chronic coronary occlusion were studied. Immediate success rates were 67%. The factors that promote successful endovascular treatment in patients with this condition were as follows: less than 2-month disease duration, well-developed intersystemic collaterals, no "bridge" collaterals.

[Results of intracoronary stenting made in different periods after diagnostic coronary angiography].

The high cost of tools and expendable materials and its associated necessity of solving organizational issues force to delay the implementation of stenting for nonmedical reasons in many cases. This gives a convenient way to evaluate how much effective and safe stenting would be made just after coronary angiography or delayed intervention would be performed and at the same time to consider the way delay in stenting may affect its clinical and angiographic results. The study covered 136 patients with coronary heart disease who had been implanted an intracoronary stent.

[Coronary angiography via femoral and radial accesses in patients with extensive atherosclerosis].

The incidence of complications and the comparative results of endovascular interventions made via femoral and radial accesses are analyzed. The study included 142 patients with coronary atherosclerosis and coronary heart disease showing a hemodynamically significant atherosclerotic lesion of at least three vascular beds. Angiography was made via femoral and radial accesses in 86 and 56 patients, respectively.

[Immediate and Remote Results of Endovascular Recanalization of Chronic Coronary Artery Occlusions].

We compared early and long-term follow-up results of balloon angioplasty and stenting of chronic coronary occlusions. The initial success rate was 75% (82 of 109 patients). Proportion of patients free of angina was 57 and 69% after successful balloon angioplasty and stenting, respectively.

[Long term results of endovascular treatment of ischemic heart disease in arterial hypertension patients].

Aim: To ascertain long-term prognosis after endovascular treatment of ischemic heart disease (IHD) in patients with arterial hypertension (AH).

Material And Methods: The trial enrolled 87 IHD patients (mean age 54 +/- 8 years) who have undergone successful transluminal balloon coronary angioplasty (TBCA) or stenting. The patients were divided into two groups.

[X-ray morphology of coronary arteries in patients with arterial hypertension in late periods after endovascular treatment].

An association of arterial hypertension (AH) and late angiographic outcomes of endovascular interventions was studied in coronary heart disease. Forty two patients with or without AH underwent repeated coronary angiography within 2 months after the procedure. The total number of restenoses was found to be significantly greater in patients with AH than in those without it.

[Quantitative and qualitative assessment of X-ray morphology of coronary restenosis after balloon angioplasty and stenting].

The study was undertaken to compare the data of quantitative angiographic analysis of early and late outcomes of intracoronary stenting (ICS) and balloon coronary angioplasty (BCA) with the X-Ray morphology of restenosis. The prospective study enrolled 67 patients undergone repeated coronary angiography 2-10 months after successful BCA. Group I included 34 patients with coronary restenosis.

[Specific features of the clinical course and angiographic pattern in chronic coronary artery occlusion].

Particular features of coronary angiography and clinical presentation of coronary artery disease have been studied in patients with chronic total coronary occlusion. Chronic total coronary occlusion is defined as TIMI 0 or TIMI I type flow in the artery for more than three days. Patients with coronary occlusion have more severe course of coronary artery disease: they more often suffer myocardial infarction and high gradations of angina.

[Long-term assessment of clinical parameters in patients with coronary heart disease after balloon angioplasty and stenting balloon angioplasty].

The aim of this study was to assess clinical parameters in patients with coronary heart disease (CHD) in the late period after balloon coronary angioplasty (BCA) and intracoronary stenting (ICS). The study included 104 patients who underwent repeated coronary angiography (CA) 2-10 months after successful coronary angioplasty. Clinical parameters were analyzed in 2 groups comparable at the moment of its performance in terms of major clinical characteristics.

[Use of heparin-coated "Jo Stent M" in patients with ischemic heart disease: first results].

The aim of the present study was to make a clinical and angiographic assessment of early outcomes of the use of heparin-coated new "Jo Stents M". The Study comprised 41 patients who were implanted a heparin-coated new "Jo Stent M". There was an immediate success in 45 (97.

[Acute occlusion of the coronary artery after transluminal balloon coronary angioplasty].

Acute occlusion of the coronary artery is one of the most grave complications of transluminal balloon coronary angioplasty (TBCA). Singling out a group of patients at risk of developing this complication is important for the definition of indications for TBCA, for prediction of its results, and selection of treatment strategy. This research was aimed at elucidation of the relationship of the clinical and angiographic factors, on the one hand, and development of acute occlusion following TBCA, on the other.