[Local EEG characteristics of the children with psychic abnormalities, examined by independent components analysis (ICA)].

The method of independent components within the range of 3-13 Hz was used for the analysis of EEG of the children with psychic abnormalities of perinatal origin. The research was undertaken while children were keeping awake with open eyes. In cases of harder developmental delay it was revealed a significant rise of θ-range power spectrum in frontal-temporal cortex areas of left hemisphere and temporal areas of right hemisphere.

[Analysis of independent components for event-related potentials from patients with an established diagnosis of schizophrenia, obsessive-compulsive and depressive disorders].

We investigated the possibility to classify data from patients with different psychiatric disorders on the base of physiological measures of the brain activity. Event-related potentials during the execution of GO/NOGO task were recorded from age matched groups of patients with schizophrenia, major depression and obsessive-compulsive disorder. Separation of independent components for event-related potentials was performed by applying Independent Component Analysis method.

[Brain structures and functional pecularities in children with mental disorders and transcranial direct current stimulation].

This research represents MRI and EEG-investigation in children with mental disorders perinatal genesis during tDCS. In 70% cases brain structures damages don't found or were minimal. On the contrary, in 77% cases α-rhythm of EEG in parietal-occipital areas was non-regular.

[Improving source localization of ERPs in the GO/NOGO task by modeling of their cross-covariance structure].

We studied 19-channel event-related potentials (ERPs) during the GO/NOGO task in 517 healthy subjects. Decomposition of multi-channel ERP into independent components was performed with a method based on modeling the cross-covariance structure of the transient response. The results show that this method allows us to obtain low-correlated components with acceptable reliability.

[Power spectra of the main EEG rhythms in children with different types of attention deficit hyperactivity disorder].

We investigated a group of children aged 9-12 years with attention deficit hyperactivity disorder (ADHD) combined type, have divided into two variants of the clinical picture of ADHD: residual-organic variant (ADH D RO) and idiopathic variant (ADHD RI). We studied the power spectral analysis in the main frequency bands in background EEG eyes closed and are open. The significant differences between both groups observed in the theta frequency band in the fronto-central and occipital leads.

[Functional biomarkers in the diagnostics of mental disorders: cognitive event-related potentials].

The article is devoted to recent researches in the field of fundamental knowledge about the mechanisms of information processing in human brain for the diagnosis of mental disorders performed in the laboratory of neurobiology for action programming of the Bechtereva Institute of Human Brain, RAS. These researches were connected with analysis of functional components for cognitive ERPs obtained in diverse behavioral conditions. The main goal of this fundamental approach is the decomposition of multi-channel ERPs into functionally different components.

[Possibility of using biofeedback for amplitude training of ERP's independent components].

The aim of this study was to investigate the possibility of voluntary training for independent component of event-related potentials in modified two-stimuli Go/NoGo test by the method of biofeedback. Subjects were 10 healthy people which were asked to increase amplitude of P3b component of event-related potentials from Go stimulus. This component is generated in parietal area and is thought to be connected with action engagement.

[Analysis of EEG characteristic at early stages of depression using method of independent components].

Independent Component Analysis (ICA) was used for 19-channel resting EEG analysis 111 patients at early stages of depressive disorder and 526 age-matched healthy subjects. Comparison of independent components power spectra in depressed patients and healthy subjects in two states: Eyes closed and Eyes open, has revealed significant differences between groups for three frequency bands: Theta (4-7.5 Hz), Alpha (7.

[The comparison of clustering methods of EEG independent components in healthy subjects and patients with post concussion syndrome after traumatic brain injury].

The comparison of three different clustering methods of 19-channels EEG independent components in 518 healthy subjects and 87 patients with post concussion syndrome after traumatic brain injury was performed to define more exact the location of sources of pathologic brain activity. Following methods of grouping were used: clustering of independent components topographies, clustering of coordinates of equivalent dipole sources corresponding to independent components topographies and sorting of independent components using extremes of equivalent source current density computed by Standardized Low Resolution Electromagnetic Tomography (sLORETA).The comparison of power spectra of independent components revealed statically significant increase of EEG power located in frontal and temporal brain areas in delta, theta and alpha frequency bands in patients with post concussion syndrome after traumatic brain injury.

[Normative EEG spectral characteristics in healthy subjects from 7 to 89 years].

EEGs were recorded at 885 healthy subjects of both sexes with age from 7 to 89 years in "eyes closed" and "eyes opened" conditions. Both average EEG power spectra and EEG independent component power spectra were computed for 20 age groups of subjects separately, and corresponding confidence intervals of average power were estimated for four frequency bands: delta, theta, alpha and beta. These quantitative data can be useful as objective criteria for diagnostics of brain dysfunctions.

[Use of transcranial micropolarization in the treatment of tension headaches].

The study was made of effectiveness of transcranial micropolarization (TSMP) in the treatment of tension headache (TH). A course of TSMP was conducted in 33 TH patients. TSMP has relieved TH, anxiety, depression.

[Transcranial micro-polarization in the treatment of ADHD in children and adolescents].

An effect of transcranial micropolarization on attention deficit hyperactivity disorder treatment in 57 children and adolescences has been studied. A higher efficacy of the method was shown: the patients revealed a significant decrease of impulsivity, hyperactivity and increase of attention (in 71-77% children).