SPECIFICS OF PRESCRIBING ANTIRETROVIRAL DRUGS IN THE TREATMENT OF HIV INFECTION.

HIV infection is one of the most acute problems of our time, characterized by slow development, prolonged course, and numerous clinical manifestations. Currently, there is a large number of drugs acting on different processes of human immunodeficiency virus replication, which constitute the group of highly active antiretroviral therapy (HAART). This article shows a theoretical review of modern HAART and analyzes the prescribed treatment regimens for patients with HIV infection.

[Efficacy of percutaneous coronary intervention in patients with ST elevation myocardial infarction and impaired glucose tolerance or diabetes mellitus].

Purpose: To assess the role of percutaneous coronary intervention (PCI) for in-hospital and one-year prognosis of ST elevation (STE) myocardial infarction (MI) patients with impaired glucose tolerance (IGT) or type 2 diabetes mellitus (T2DM).

Material And Methods: This registry study included 601 STEMI patients admitted to hospital within 24 hours after STEMI onset during one year. According to medical history, dynamics of glycemia and results of oral glucose tolerance test patients were divided into 3 groups: (1) without disturbances of carbohydrate metabolism (DCM), (2) with IGT and (3) with T2DM.

[Multifocal atherosclerosis as a factor of unfavorable prognosis in patients with ST elevation myocardial infarction and type 2 diabetes mellitus].

Multifocal atherosclerosis (MFA) and diabetes mellitus (DM) determine less favorable course of acute vascular catastrophes. We analyzed dependence of one year prognosis of patients with myocardial infarction (MI) with and without DM on the presence of multifocal atherosclerosis. The analysis showed that number of cardiovascular complications increased with increase of degree of severity of atherosclerosis.

[Level of glycemia as a marker of prognosis in patients with myocardial infarction with ST segment elevation].

High mortality of patients with myocardial infarction (MI) determines pursuit of novel markers of risk as well as predictors of development of unfavorable outcome. The question of the role glycemia in development of cardiovascular complications in patients with acute coronary syndrome remains open. Analysis of in hospital mortality revealed U-shaped relacion ship between level of glycemia at admission and mortality in patients with ST elevation MI combined with diabetes mellitus (DM), and presence of direct linear relation - in patients without DM.

[State of the mitral valve and myocardial contractile capacity in patients who have had a myocardial infarct according to echocardiographic data].

Echocardiography was conducted in patients who had suffered from myocardial infarction (47 were examined in the subacute period of myocardial infarction and 23 in more remote periods) with signs of mitral insufficiency and 31 patients with no signs of mitral insufficiency (they were examined in the subacute period of myocardial infarction). It was found that after myocardial infarction the contractility of the heart muscle is diminished to a greater extent in patients with signs of mitral insufficiency than in the others. In patients with mitral insufficiency symptoms of circulatory insufficiency were revealed more frequently.