[Topographic rapid pH-metry. Possibilities and prospects of use in the functional diagnosis of stomach diseases].

More than 700 patients were examined by rapid intragastric pH-metry with the use of original pH-microtubes and K -2 device. Numerous advantages of the method were observed: the tube is easy to introduce into the stomach, the procedure is short, there are no contraindications against it, it involves no complications, pH values can be recorded along the entire stomach (30 cm) with just 1 cm intervals (topographic pH-metry). Diagnostic potentialities of the method are limited because there are no standard pH values for each specific site of the stomach under conditions of basal and stimulated secretion.

[The effect of calcium antagonists and beta-adrenoblockaders on disordered stomach functions in patients with duodenal peptic ulcer].

The effect of a single dose of nifedipine or propranolol hydrochloride on gastric acid production and motility has been assessed in 90 duodenal ulcer (DU) patients having the relapse. Intragastric pH-metry showed that the drugs in a dose 20 mg significantly inhibit basal acid production. As indicated by electrogastromyography, nifedipine effect on gastric motility depends on its baseline level.