[The combined radionuclide diagnosis of rectal cancer recurrences].

Of 153 patients with confirmed rectal cancer CEA was recorded in 139 (90.8%); erroneous results were noted in 14 (9.2%) patients; in scintigraphy with 67Ga-citrate and 111In-bleomycin diagnoses coincided in 147 (96.

[X-ray-radionuclide diagnosis of lung cancer metastases to the intrathoracic lymph nodes].

The authors conducted a comparative study of x-ray and radionuclide investigations of 203 lung cancer patients. The potentialities of each method were shown for metastatic lesions of the lymph nodes of the root of the lungs and mediastinum. The results obtained are indicative of the fact that these methods improve preoperative diagnosis of regional metastatic spreading in lung cancer that is very important for a design of therapeutic tactics.

[Thermography with glucose loading in the examination of women at high risk of developing breast cancer].

Thermography of the breast with pharmacological GTT was performed in 260 women; cancer was diagnosed in 150 of them, benign breast diseases in 110. A significant increase in temperature asymmetry after GTT was shown in breast cancer patients as compared to patients with benign diseases. Data on the sensitivity of the mammographic and thermographic methods to identify risk groups were presented.

[Scintigraphy with tumoritropic radiopharmaceutical preparations in the diagnosis of cancer of the large intestine].

The authors represented the results of scintigraphic investigation to define the spreading of colon cancer in 78 patients. Of 21 patients in whom the investigation with 67Ga-citrate was performed in the preoperative period, RP accumulation was noted in 18, false-positive results were noted in 3 patients. During the investigation of 41 patients with 111In-bleomycin false-positive results were noted in all the cases.

[Radionuclide and thermographic diagnosis of regional metastases of cancer of the tongue and larynx].

To study the potentialities of scintigraphy with 67Ga-citrate and thermography these investigations of the neck lymph nodes were performed in 120 patients with cancer of the tongue and larynx. All the patients were divided into 4 groups with relation to the clinical manifestations of the nodes. The sensitivity of both methods was 87.

[Immunoscintigraphy of cancer of the ovaries and colon using labeled monoclonal antibodies].

Immunoscintigraphy with labeled monoclonal antibodies for investigation of patients with ovarian and colon adenocarcinoma is a highly informative method which can be used for immunovisualization of primary tumor foci, their recurrences and metastases. A possibility to estimate specific tumor tissue activity was shown to be the advantage of immunoscintigraphy as compared to other special topical methods of investigation. High blood concentrations of tumor antigens did not deteriorate significantly the quality of visualization of tumor foci using labeled monoclonal antibodies.

[Scintigraphy of the mediastinum using 67Ga citrate in lymphogranulomatosis in children].

Scintigraphic semiotics of the involvement of the intrathoracic lymph nodes in children with Hodgkin's disease permitted differentiated assessment of the state of each group of the mediastinal lymph nodes and root of the lung over time. Knowledge of the characteristic features of 67Ga-citrate scintigraphic distribution with relation to the mediastinum after therapeutic measures makes it possible to exclude false positive results and to define the correct time for monitoring.

[Radionuclide diagnosis of vasculogenic impotence].

Pathogenesis of vasculogenic impotence is most adequately revealed by modern methods of the investigation of the hemodynamic mechanisms of erection with the enhancement of arterial perfusion of corpora cavernosa by artificial sexual stimulation. Radionuclide diagnostic methods effectively differ from the methods of radiocontrast phalloangiography by the simplicity of investigation and the absence of traumatism for a patient. The authors have proposed a mathematical model of a process of filling in the functioning volume of the penile vascular bed with a radiopharmaceutical preparation against the background of erection induced by intracavernous administration of papaverine hydrochloride solution.

[Emission computed tomography in the diagnosis of lung diseases].

Investigations of pulmonary perfusion with 99m Tc-MMA by the method of emission computed tomography (ECT) were conducted in 172 patients with different pulmonary diseases. The authors described ECT procedure of the lungs and scinti-tomographic symptomatology typical of the normal lungs and different types of pulmonary pathology (lung cancer, benign tumors, metastases and chronic inflammatory pulmonary processes). A high sensitivity of ECT as compared to poly-positional scintigraphy was shown.

[Scintigraphy with 67Ga-citrate and 111In-bleomycin in cancer of the rectum].

Scintigraphy with 67Ga-citrate and 111In-bleomycin was performed in 26 patients with primary rectal cancer, 176 patients with suspected recurrent tumors, and in 34 patients without clinicoroentgenological signs of cancer recurrence. A focus of higher accumulation of these radionuclides in the rectal area was recorded in all 26 patients. Of 176 patients with symptoms of recurrence tumors were detected by means of ultrasonic and computed tomography of the small pelvis in 158 patients.

[Thermography and radionuclide scintigraphy in reconstructive plastic operations following radical mastectomy].

Thermography is quite an informative and reliable method of examination of patients after reconstructive-plastic breast operations. It makes it possible to assess, with a sufficient degree of assurance, the blood circulation in a skin-muscular graft of the broadest muscle of the back, to diagnose capsule constrictive fibrosis, to detect foci of hyperthermia at the edge of endoprosthesis in the presence of bulky formations hidden by an implant, and can be recommended for the screening of such patients. In some cases scintigraphy makes it possible to differentiate between tumor and non-tumor origin of foci of lesions detected in endoprosthesis.

[Thermography and computed tomography in the diagnosis of cancer recurrence after rectal extirpation].

The results of thermography and computed tomography of 168 patients following rectum extirpation for cancer were analysed. Of them 116 had symptoms of cancer recurrence and 52 with a poor prognosis were without signs of recurrence. In the 1st group thermography made it possible to record recurrences in 106 (91.

[Radionuclide determination of the extent of the tumor process in patients with esophageal cancer].

Scintigraphy with 67Ga-citrate and 111In-bleomycin was conducted in 32 esophageal cancer patients, 4 patients with benign esophageal tumors and in 3 patients with scarry-ulcerous esophagitis. A raised accumulation of the radiopharmaceutical (RP) in the esophagus, in 4 cases in the retroperitoneal paraaortic lymph nodes in which a metastatic image was confirmed at computed tomography and diagnostic laparotomy, was observed in all cancer patients. No regularities in the intensity of the accumulation of both radiopharmaceuticals in the esophageal tumor with relation to its histological structure were detected.

[Thermography in the diagnosis of retinoblastoma in children].

The authors presented the results of thermographic examination of children with suspected retinoblastoma (30 primary examined patients and 30 patients examined to assess therapeutic efficacy). The results of the examination showed the relationship of the intensity and extent of the hyperthermia zone with tumor stage. The usefulness of the thermographic method for efficacy assessment was shown.

[Thermography in the diagnosis of recurrences of rectal cancer].

Thermography results of 126 patients were analysed for the diagnosis of recurrences of rectal cancer. Sixteen patients were examined after radical operations for rectal cancer without signs of recurrence to study the features of a thermal regimen in this area. The examination included thermoscopy, thermography and distant thermometry.

[Scintigraphy with 111In-bleomycin in the diagnosis of recurrences of rectal cancer].

Altogether 76 patients were examined using scintigraphy with 111In-bleomycin. Clinicoroentgenological diagnosis of recurring rectal cancer was confirmed in 62 of them. Fourteen patients were without signs of recurrence.

[Carcinoembryonic antigen and hormonal polypeptides in patients with lung cancer].

The paper is concerned with the evaluation of the diagnostic value of a tumor marker complex determined by in vitro analysis at primary diagnosis of lung cancer, during early postoperative follow-up and subsequent monitoring for early detection of disease progression.

[Changes in the regional indices of ventilation and perfusion in lung cancer patients during treatment].

A total of 27 patients with central lung cancer and 43 patients with peripheral lung cancer of various sites were examined after surgical intervention on a multichannel unit using 133Xe. The regional distribution of alveolar ventilation and perfusion blood flow were evaluated in the preoperative period as well as at varying times after operation. Statistical analysis of the results has shown that a significant decrease in the ventilation and blood flow is observed in the zone with a focus of lesion in the preoperative period.

[67Ga-citrate in the differential diagnosis of benign lesions and lung cancer].

A total of 77 patients with tumors and benign lesions of the lungs were examined. In addition to the x-ray method the use of a study with 67Ga-citrate was found appropriate in the differential diagnosis of spheroidal lesions of the lungs.

[Radionuclide and thermographic diagnosis of head and neck neoplasms].

Radionuclide and thermographic studies using 67Ga-citrate and 111In-bleomycin were performed in 129 patients with laryngeal cancer, chemodectoma of the neck, retinoblastoma, rhabdomyosarcoma of the orbital and facial soft tissues and cancer of the tongue. Elevated amounts of the radiopharmaceutical drug were found in patients with tumors. In thermographic studies higher thermogenic activity corresponding to the tumor was noted.