[Use of a neodymium lasers for fluorescent diagnosis and photodynamic destruction of tumors].

Fluorescence and photodynamic destruction of tumor tissues containing hematoporphyrin derivative was studied during excitation by II and III harmonics of AY:Nd(3+)-laser. This laser system can be effectively used for diagnosis of malignant tumours and photodynamic therapy.

[The distribution of hematoporphyrin derivatives in the animal body].

The pharmacokinetic distribution of haematoporphyrin derivative (HPD) and synthetic oligomeric haematoporphyrin (OG) which showed various lipophilicity was studied in animal tumor and normal tissues. The accumulation of dyes in tissue and their tumor-seeking capacity depended on the degree of polymerization, lipophilicity, and ratio of dye components. The difference in the absolute concentrations of HPD and OG (6.