[Metabolic profiling for characteristics of Trichoderma from buried soils].

Previously, 135 strains of Trichoderma isolated from buried soils of Tatarstan have been identified as T. asperellum, T. viride, T.

[Development of paste-type food for experiments with mice onboard unmanned spacecrafts].

One of the crucial issues of handling animals in space flight is availability of food and water supply systems. However, water supply for animal experiments onboard unmanned spacecrafts is a particularly formidable problem. To maintain laboratory mice in space flight, a paste-type food was formulated on the basis of the standard extruded combined food for laboratory rodents (PK-120) with a 18.

[Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight].

It was stated that spaceflight factors (SFF) affect the chromosomal DNA interchange during Streptomyces crossing. Cross polarity and primary input of a parent chromosome fragment in recombinant generation imply a more lasting cells contact in microgravity and a broader horizontal transport of genetic material. SFF had no effect on recombination frequency and mutation in a model of parental auxotrophic markers reversion to prototrophism.

[The content of protein S-100 and tumor-necrosis factor-alpha in the serum of patients with discirculatory encephalopathy].

To study the content of protein S-100 and tumor-necrosis factor-alpha (TNF-alpha) in the serum of patients with discirculatory encephalopathy (DE), stages I and II, 108 patients have been examined. The diagnosis of vascular damage of the brain has been confirmed by ultrasound and MRI-examination. Patients with DE, stage II, had significantly higher levels of protein S-100 and TNF-alpha (0.

[Investigation of dysbiosis developing during "dry" immersion and methods of correction].

Dysbiotic shifts in intestinal and integumentary microflora were studied in 10 test-subjectes during 7-day "dry" immersion. Essentially every test-subject reduced significantly fecal lactoflora and developed dysbiotic shifts in the microbial landscape of various types of integument. Pharyngeal microflora was analyzed in 22 normal volunteers for 7-day "dry" immersion.

[Effect of short-term application of a lactate-containing probiotic on the pharyngeal microflora in healthy subjects].

Daily dynamics of pharyngeal microflora was evaluated in the absence of preventive treatment and using a local lactate-producing probiotic preparation during 24 hour-long simulated microgravity. The study showed that the short-term application of the local lactate-producing probiotic (four times daily) significantly reduced titers of opportunistic pathogenic microflora and increased the amount of symbionts in the pharynx.

[A comparison of efficacy of different modalities of treatment for locally-advanced and metastatic non-small lung cancer].

The paper evaluates the efficacy of different modalities of treatment for locally-advanced and metastatic non-small lung cancer (NSLC) (1,316 pts.). Adjuvant chemotherapy was followed by an elevation of median of survival from 14 to 21.

[Use of endotracheobronchial surgery in conjunction with radiochemotherapy for advanced non-small lung cancer].

The paper deals with data on 191 endotracheobronchial surgeries (ETBS) in 153 patients with advanced non-small lung cancer involving breath obstruction (stage IIb--13.7%, III--71.9%, IV--14.

[Experimental grounds for administration of probiotic drugs in conditions of hydroweightlessness].

We studied pharyngeal microflora in 22 healthy volunteers after 7-day dry immersion. For prophylactic pharyngeal dysbiosis, we used two probiotic drugs: oral -- "lactobacterin dry" and local --"lactobacterin immobilized on collagen". Administration of oral probiotic was accompanied with growth of pharyngeal opportunistic microflora preventing translocation of intestinal microflora.