[Calcitonin: properties and methods of production].

Calcitonin structure, biological activity, formation in organism and methods of production including isolation from natural sources, chemical synthesis and genetic engineering methods are reviewed.

[Effect of peptides--structural analogs of NH2-terminal sites of fibrin alpha- and beta-chains--on specific binding of the NH2-terminal disulfide bond of fibrin with fibrinogen].

Peptides Gly-Pro-Arg-Pro and Gly-His-Arg-Pro (fibrin alpha- and beta-chain NH2-terminal analogs, respectively) are studied for their effect on fibrinogen (F) and fibrin NH2-terminal disulphide knot (N-DSK) specific binding. Both peptides are found to inhibit the formation of soluble and insoluble F-N-DSK-complexes through inhibition of the interdomain D-E-binding. Gly-Pro-Arg-Pro is much more potent inhibitor than Gly-His-Arg-Pro.

[Toxicological characteristics of disodium salt of N-lauroyl-L-glutamic acid--a surface-active agent used in the food processing industry].

To synthesize the disodium salt of N-lauroyl-L-glutamic acid (LG-Na2), use was made of the chloranhydride method with some modifications. The yield of the product was 85%. LG-Na2 possesses good surface-active properties and an emulsifying effect.

[Removal of surface-active substances from proteins by reversible immobilization on water-insoluble carrier].

Techniques for removing of surface-active substances from cysteine and cystine-containing proteins preliminarily immobilized by thiol-disulfide exchange on water-insoluble carrier, followed by protein transfer into solution, as examplified in sodium dodecyl sulfate, cetyltrimethylammonium bromide and bovine serum albumin are described. This procedure may be used to remove any sort of material non-covalently bound to protein.