Publications by authors named "Itziar Gonzalez Gomez"

Article Synopsis
  • 3D bioprinting utilizes bioinks that mix biological and synthetic materials, but choosing the right cell-material combo is challenging due to varying optimal conditions.
  • Plasma-loaded alginate and alginate/methylcellulose inks were tested for their properties, finding that a specific mix (3% SA and 9% MC) had the best stacking ability and recovery.
  • A cell-laden bioink was printed using an Inkredible 3D printer, producing viable cylindrical constructs that showed good cell proliferation, demonstrating the effectiveness of the PANC-1/P-Alg/MC bioink for creating pancreatic tumor models.
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The analysis of cell motion in an acoustic field is of interest as it can lead to new methods of cell separation, isolation and manipulation for diagnosis and treatment of diseases. Studies of the motion of different species of Leishmania parasites during exposure to ultrasonic standing waves in a microfluidic device allowed identification of acoustic responses of these parasites in their promastigote and amastigote forms. Both forms exhibited a positive acoustic contrast factor and were driven toward the pressure node established in the center of the channel by the acoustically induced radiation force (F).

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Ultrasounds (US) are a non-ionizing mechanical wave, with less adverse effects than conventional pharmacological or surgical treatments. Different biological effects are induced in tissues and cells by ultrasound actuation depending on acoustic parameters, such as the wave intensity, frequency and treatment dose. This non-ionizing radiation has considerable applications in biomedicine including surgery, medical imaging, physical therapy and cancer therapy.

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