Publications by Itzel Uribe-Gonzalez

Publications by authors named "Itzel Uribe-Gonzalez"

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Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles.

Rogelio Jiménez-Juárez Wendy Cruz-Chávez Nayeli de Jesús-Ramírez Guadalupe Ivonne Castro-Ramírez Itzel Uribe-González

Front Chem

June 2020

The appearance of drug-resistant strains of and the dramatic increase in infection rates worldwide evidences the urgency of developing new and effective compounds for treating tuberculosis. Benzimidazoles represent one possible source of new compounds given that antimycobacterial activity has already been documented for some derivatives, such as those bearing electron-withdrawing groups. The aim of this study was to synthesize two series of benzimidazoles, di- and trisubstituted derivatives, and evaluate their antimycobacterial activity.

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- Itzel Uribe-Gonzalez's research primarily focuses on the synthesis and evaluation of benzimidazole derivatives, specifically 2,5-disubstituted and 1,2,5-trisubstituted compounds, for their potential antimycobacterial activity against drug-resistant strains of tuberculosis.
- The 2020 article published in "Front Chem" highlights the urgency of finding effective new treatments for the rising rates of tuberculosis, emphasizing the importance of investigating compounds with documented antimycobacterial properties, particularly those with electron-withdrawing groups.
- The findings demonstrate that the synthesized benzimidazole derivatives show promise as new antimycobacterial agents, potentially contributing to the development of effective treatments for tuberculosis infections.

Publications by authors named "Itzel Uribe-Gonzalez"

Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles.

Synopsis of recent research by authors named "Itzel Uribe-Gonzalez"