Publications by authors named "Itil I"

Study Objective: To evaluate the effect of concomitant hysterectomy on perioperative outcomes in patients who underwent obliterative pelvic organ prolapse (POP) surgery.

Material And Methods: This retrospective study included 95 consecutive patients with no prior hysterectomy who underwent obliterative surgery for POP between February 2015 and April 2021. Perioperative outcomes of colpocleisis without hysterectomy (C) and colpocleisis with hysterectomy (CH) were compared.

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Aims: This study aims to describe our transvaginal natural orifice transluminal endoscopic surgery (vNOTES) technique for ectopic pregnancy that can be performed using conventional laparoscopic equipment with the addition of a self-constructed pessary port and to evaluate the safety, feasibility, and outcomes of the technique.

Methods: This is a retrospective study evaluating outcomes of patients who underwent vNOTES for ectopic pregnancy (n = 21) between August 2019 and April 2021.

Results: Twenty-one patients underwent vNOTES as intended without any intraoperative complications.

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Study Objective: To describe a vaginal approach combining vaginal hysterectomy (VH) with transvaginal natural orifice transluminal endoscopic surgery (vNOTES) bilateral salpingo-oophorectomy (BSO) for hysterectomy in transgender men and to evaluate the feasibility, safety, and surgical outcomes of this approach in comparison with laparoscopy.

Material And Methods: Retrospective cohort study comparing outcomes of the vaginal approach (n = 45) and laparoscopy (n = 45) in transgender men undergoing hysterectomy between May 2017 and June 2020.

Results: There was one intraoperative complication (bladder injury) in the laparoscopy group, which was the reason for the only conversion from the initial surgical approach.

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Study Objective: To evaluate the impacts of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) on the hysterectomy route and concomitant adnexal surgery at the time of vaginal hysterectomy (VH).

Material And Methods: This retrospective study analyzed all hysterectomies performed for benign indications between 1 January 2017 and 31 December 2019. The period preceding the first case of VH and vNOTES BSO was considered as Pre-vNOTES.

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Article Synopsis
  • Placenta accreta spectrum (PAS) is a serious obstetric condition linked to high rates of morbidity and mortality, prompting the need for predictive models to assess possible clinical outcomes.
  • An international study, PAS-ID, analyzed data from 727 women diagnosed with PAS between 2010 and 2019, utilizing machine learning to create two predictive models based on various clinical features.
  • Results showed high predictive accuracy, with models identifying significant factors like parity and placental site, indicating that machine learning can effectively assess individual risk and guide management strategies for women with PAS.
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Objective: To create a model for prediction of success of uterine-preserving procedures in women with placenta accreta spectrum (PAS).

Methods: PAS-ID is a multicenter study that included 11 centers from 9 countries. Women with PAS, who were managed between January 1, 2010 and December 31, 2019, were retrospectively included.

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Article Synopsis
  • This study outlines a simplified two-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES) and provides video evidence from its application.
  • The patients involved were a 27-year-old with ovarian torsion and a 25-year-old with an ectopic pregnancy, both of whom underwent diagnostic and therapeutic procedures via vNOTES.
  • Key steps included creating a colpotomy, confirming the diagnosis using an endoscope, and performing specific surgical interventions while ensuring safety and hemostasis.
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Objective: To demonstrate a case of left tubal stump pregnancy successfully treated using our 2-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES).

Design: Demonstration of the technique using surgical video footage.

Setting: Tertiary university hospital.

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Aims: To evaluate the relationship between overactive bladder (OAB) and systemic atherosclerosis in a cohort of women.

Methods: In this case-control study, we assessed atherosclerosis indicators, such as Framingham risk scores and carotid and femoral artery intima-media thickness, and evaluated possible bladder wall responses to atherosclerosis using endovaginal color Doppler ultrasound and the detection of urinary cytokines in women with OAB and in controls. Quantitative assessment of blood perfusion at the bladder neck was performed using a method that allows for the dynamic monitoring of flow in a predefined region of interest at every point of the cardiac cycle.

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Objective: To evaluate the effect of atherosclerosis on the storage and voiding symptoms of the bladder in women with overactive bladder (OAB).

Study Design: We retrospectively reviewed the charts of women with OAB who were evaluated between 2013 and 2015 in our urogynecology unit. Charts were assessed for history, examination findings, urinary diary, quality of life (QOL) questionnaires, urodynamic studies (UDSs), and four main risk factors for atherosclerosis: hypertension, diabetes mellitus, smoking, and hyperlipidemia.

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Objective: To determine whether symptoms of urinary incontinence is reduced by pelvic floor muscle training, to determine whether urinary incontinence can be totally eliminated by strengthening the pelvic floor muscle to grade 5 on the Oxford scale.

Design: Prospective randomized controlled clinical trial.

Setting: Outpatient urogynecology department.

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Objective: The purpose of our study is to determine whether there is a difference in pelvic floor muscle strength attributable to pelvic floor muscle training conducted during different stages of menopause.

Methods: One hundred twenty-two women with stress urinary incontinence and mixed urinary incontinence were included in this prospective controlled study. The participants included in this study were separated into three groups according to the Stages of Reproductive Aging Workshop staging system as follows: group 1 (n = 41): stages -3 and -2; group 2 (n = 32): stages +1 and -1; and group 3 (n = 30): stage +2.

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Objective: To evaluate the relation between overactive bladder (OAB) and sexual dysfunction in sexually active nurses without stress urinary incontinence and pelvic organ prolapse.

Design: Prospective, observational study.

Setting: Tertiary care center.

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Objective: To determine the association between mode of delivery, parity, and pelvic organ prolapse, as assessed by the pelvic organ prolapse quantification system.

Design: Cross-sectional study.

Setting: Tertiary referral center, Turkey.

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Objective: To evaluate the quality of life and surgical outcomes in women who had undergone colpocleisis.

Study Design: This was a prospective small cohort study conducted between August 2010 and September 2011. Twelve women with pelvic organ prolapse were offered obliterative vaginal surgery and were informed about the surgical procedure.

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Aim: To examine the association between placenta previa and adverse perinatal outcomes such as low birth weight, preterm delivery, stillbirth and fetal growth restriction (FGR).

Methods: This retrospective cohort study includes 12,034 delivered pregnant women who were recruited for the study between 2004 and 2010 in Ege University Hospital. Data were collected by browsing the clinic's archives.

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Objective: To determine the relationship between overactive bladder symptoms and urodynamic verification of overactive bladder.

Material And Methods: Between June 2011 and November 2011, 159 patients underwent urodynamics (UDS) at our urogynecology unit in the Ege University Hospital. Of these, 95 patients who complained of urgency, did not have any overt neurological diseases, bladder outlet obstruction and did not take any medication affecting the lower urinary tract function were evaluated.

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The purpose of this study was to assess the prevalence of female urinary incontinence (UI) and risk factors of bothersomeness and help-seeking behavior of hidden female UI in urology and obstetrics and gynecology outpatient clinics. This multicentric and cross-sectional study was conducted as a part of the Turkish Overactive Bladder Study. Female patients (n = 5,565) who were referred with complaints other than UI and overactive bladder symptoms were surveyed using the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) with supplementation of five more questions.

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Objective: The aim of the study was to determine mammographic breast density changes during raloxifene therapy in postmenopausal patients

Materials And Methods: Fifty-five cases who were using raloxifen therapy were included in this retrospective analysis. Raloxifene was given for osteopenia and osteoporosis according to low bone mineral density measured by dual-energy X-ray absorptiometry (DEXA). None of the patients were using hormone replacement therapy 12 months before the initiation of raloxifene treatment or during the study.

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The aim of this study is to evaluate the changes in Doppler resistive index (RI) and plasma creatinine and magnesium concentrations after unilateral ureteral obstruction in a rabbit model. Fourteen adult female rabbits were used in this study. In seven rabbits, the left ureter was ligated with silk suture, and the control group was sham operated.

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Objective: To investigate the effect of Bacillus Calmette-Guerin (BCG) vaccine on peritoneal implantation of endometrial tissue in rats.

Methods: Forty sexually mature virgin Wistar albino rats weighing 190-200 g were randomly assigned (double blind) to two groups. The rats in the first group were vaccinated with 0.

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Objective: The aim of the study was to determine the role of perineal sonography in diagnosis of stress urinary incontinence.

Materials And Methods: Thirty patients with stress urinary incontinence and 17 age-matched control patients were included in the study. Perineal sonography was carried out in both groups to evaluate the role of this technique in the diagnosis of stress urinary incontinence.

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Objective: The aim of this study was to determine the changes in circulating T-cell subpopulations, B cells and natural killer cells in patients with imminent preterm labour.

Methods: Thirty-five pregnant patients with imminent preterm labour and 35 women with uncomplicated pregnancies were included in the study. The gestational ages of the patients ranged from 28 to 36 weeks in both groups.

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Objective: The objective of this study is to demonstrate the distribution of extracellular matrix components of fibronectin, laminin and collagen type IV in the materno-fetal boundary zone of the developing mouse placenta.

Material And Methods: Mice fetuses and placentas were removed serially every day until the 19th gestational day. Implantation sites were processed and stained by an immunohistochemical method by specific antiserums to fibronectin, laminin and collagen type IV.

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