Synopsis of recent research by authors named "Itaru Narihara"
- Itaru Narihara's research primarily investigates the behavioral and neurophysiological characteristics of schizophrenia using animal models, particularly focusing on vocalizations and auditory processing in rats subjected to inflammatory cytokine-induced conditions.
- Key findings include the observation that these animal models exhibit self-triggered vocalizations akin to those found in schizophrenia patients, as well as impairments in auditory recognition, such as mismatched negativity (MMN), which is relevant for understanding cognitive deficits associated with the disorder.
- The studies underscore the potential of using cytokine models, specifically involving epidermal growth factor (EGF), to replicate core symptoms of schizophrenia, advancing the understanding of its neurobiological underpinnings and offering a platform for further research into therapeutic interventions.
