Publications by authors named "Itamar Toren"

Article Synopsis
  • - The increase in Crohn disease (CD) cases, especially with urbanization and globalization, is more related to environmental factors rather than genetics, suggesting changes in lifestyle impact gut health.
  • - The SOURCE study examined diet, microbiome, and genetic expression among newly diagnosed CD patients and controls from rural and urban settings in China and Israel to uncover links between lifestyle changes and CD.
  • - Findings reveal that time spent in urban environments alters gut bacteria and metabolites in rural residents, with specific dietary factors like coffee and vitamin D showing potential protective roles against CD-related changes.
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Spinal cord injury (SCI) is a devastating event that significantly changes daily function and quality of life and is linked to bowel and bladder dysfunction and frequent antibiotic treatment. We aimed to study the composition of the gut microbiome in individuals with SCI during the initial sub-acute rehabilitation process and during the chronic phase of the injury. This study included 100 fecal samples from 63 participants (Median age 40 years, 94% males): 13 cases with SCI in the sub-acute phase with 50 longitudinal samples, 18 cases with chronic SCI, and 32 age and gender-matched controls.

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